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Apocynin (Synonyms: Acetovanillone)

Cat. No.: HY-N0088 Purity: 99.86%
Data Sheet SDS Handling Instructions

Apocynin is a selective NADPH-oxidase inhibitor with IC50 of 10 μM.

For research use only. We do not sell to patients.
Apocynin Chemical Structure

Apocynin Chemical Structure

CAS No. : 498-02-2

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO $55 In-stock
1 g $50 In-stock
5 g $80 In-stock
10 g   Get quote  
50 g   Get quote  

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Description

Apocynin is a selective NADPH-oxidase inhibitor with IC50 of 10 μM. apocynin is an intracellular inhibitor of the assembly of NADPH oxidase in neutrophils and eosinophils and that apocynin requires conversion by peroxidases to exert its inhibitory effec [1] Apocynin can decrease the production of superoxide (O(2)(-)) from activated neutrophils and macrophages. Apocynin, after metabolic conversion, inhibits the assembly of NADPH-oxidase that is responsible for reactive oxygen species (ROS) production.[2] NADPH-oxidase is an enzyme responsible for reactive oxygen species production (ROS) and inhibition of this enzyme represents an attractive therapeutic target for the treatment of many diseases. [3]

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References
Preparing Stock Solutions
Concentration Volume Mass 1 mg 5 mg 10 mg
1 mM 6.0179 mL 30.0897 mL 60.1793 mL
5 mM 1.2036 mL 6.0179 mL 12.0359 mL
10 mM 0.6018 mL 3.0090 mL 6.0179 mL
Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

166.17

Formula

C₉H₁₀O₃

CAS No.

498-02-2

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

10 mM in DMSO

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

Purity: 99.86%

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Product Name:
Apocynin
Cat. No.:
HY-N0088
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