Others

2,3,4,5-Tetrahydro-3-(trifluoroacetyl)-1,5-methano-1H-3-benzazepine-7,8-diamine is a drug intermediate for synthesis of various active compounds.

4-(4-Aminophenyl)morpholin-3-one is a drug intermediate for synthesis of various active compounds.

Pentynoic acid STP ester sodium is a click chemistry reagent containing a terminal propargyl group and a STP ester group. Pentynoic acid STP ester sodium is suitable for protein modification.

Norflurazon (SAN 9789) is a bleaching herbicide. Norflurazon can block carotenoid biosynthesis by inhibiting phytoene desaturase activity.

Adenosine 5'-diphosphate (Standard) is the analytical standard of Adenosine 5'-diphosphate. This product is intended for research and analytical applications. Adenosine 5'-diphosphate (Adenosine diphosphate) is a nucleoside diphosphate. Adenosine 5'-diphosphate is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate induces human platelet aggregation and inhibits stimulated adenylate cyclase by an action at P_2T-purinoceptors. In Vitro: Adenosine 5'-diphosphate consists of the pyrophosphate group, the pentose sugar ribose, and the nucleobase adenine. Adenosine 5'-diphosphate is the product of ATP dephosphorylation by ATPases. ADP is converted back to ATP by ATP synthases. ATP is an important energy transfer molecule in cells. Adenosine 5'-diphosphate is utilized in a wide number of cellular processes, including respiration, biosynthetic reactions, motility, and cell division.

IQ 1 is a Wnt/β-catenin/CBP signalling sustainer. IQ 1 maintains long-term expansion of Wnt/β-catenin-driven mouse embryonic stem cells (ESCs) and prevents spontaneous differentiation by enhancing β-catenin/CBP-mediated transcription and preventing conversion to β-catenin/p300-mediated transcription. IQ-1 regulates Wnt signalling by interacting with PR72/130. IQ 1 can be used in study of ESCs expansion.

AMPPD (Lumi-Phos Plus; Lumigen PPD) is a chemiluminescent substrate for alkaline phosphatase (APase). AMPPD is hydrolyzed by APase to generate an unstable dioxetane intermediate, and the intermediate releases a chemiluminescent signal when it decomposes. The luminescent signal of AMPPD can be detected by highly sensitive equipment, thereby achieving quantitative analysis of the target molecule. AMPPD can be used in ultrasensitive enzyme-linked immunosorbent assays (such as quantitative detection of human tissue kininogen), chemiluminescent detection of proteins and nucleic acids, and other fields.

S9-A13 is a potent and selective inhibitor SLC26A9, with the IC₅₀ of 90.9 nM, without inhibiting other members of the SLC26 family such as SLC26A3, SLC26A4, and SLC26A6. S9-A13 can inhibits SLC26A9 Cl^- currents in cells that lack expression of CFTR.

Hydroxy Itraconazole (R-63373) is an active metabolite of Itraconazole (ITZ), which is a triazole antifungal agent.

SRI-42127 is a HuR translocation inhibitor. HuR is an RNA regulator that binds to AREs, and HuR translocations promote the production of inflammatory cytokines in glial cells. However, SRI-42127 can destroy mRNA stability and inhibit gene promoter activation. SRI-42127 also inhibits microglial cell activation and attenuates recruitment/chemotaxis of neutrophils and monocytes.

ONO-0740556 is a potent Gi-coupled human lysophosphatidic acid receptor 1 (LPA1) agonist with an EC₅₀ value of 0.26 nM.

bisSP1 is an antibody-drug conjugate linker (ADC Linkers). bisSP1 is also a click chemistry reagent that undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Alkyne groups, and strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

Puromycin-bis (PEG2-amide)-Biotin (Compound 3P) is a binding molecule. Puromycin-bis (PEG2-amide)-Biotin binds to ribosome-RNA complexes within single cells. Puromycin-bis (PEG2-amide)-Biotin is used for single-cell translatome sequencing.

BSA Protein, Acetylated (Bovine Serum Albumin, Acetylated) is a polypeptide of known structure with strong antigenicity. BSA Protein, Acetylated produced a significant immune response, validating the accuracy and reliability of the experimental method. BSA Protein, Acetylated can be used as a positive control substance in ELISA or WB experiments, and can be used in experiments with acetylated lysine monoclonal or polyclonal antibodies. BSA Protein, Acetylated also improves encapsulation efficiency at low concentrations of PLGA, a polymer for biopharmaceutical delivery with biocompatibility, degradability, and controlled release properties.

Ribitol is a crystalline pentose alcohol formed by the reduction of ribose. Enhancing the flux of D-glucose to the pentose phosphate pathway in Saccharomyces cerevisiae for the production of D-ribose and ribitol.

BODIPY 630/650X is a red fluorescent dye that targets amine groups. BODIPY 630/650X displays excitation/emission maxima of 630/650 nm, respectively. BODIPY 630/650X can be used to covalently label proteins, antibodies, or other amine-containing biomolecules for detection and imaging.

Lignin (Lignine) is a natural complex biopolymer with biodegradable and biocompatible. Lignin is the main component of plant cell walls and is a renewable aromatic polymer. Lignin has strongly antioxidant activity.

1-Methyladenine is a gonad maturation-promoting regulator. 1-Methyladenine is produced in testes and ovarian follicle cells of starfish under the induction of gonad-stimulating substance (GSS). 1-Methyladenine promotes starfish oocyte maturation and spawning, and modifies bases that regulate DNA structure. 1-Methyladenine converts T-A base pairs in double-stranded DNA into non-disruptive T (anti)m1A (syn) Hoogsteen conformation. If this conformational base is not repaired in a timely manner, 1-Methyladenine transforms into cytotoxic DNA damage and blocks the replication process.

6-NBDG is a fluorescent glucose analogue, it can be used for fluorescence imaging and monitoring glucose transport and uptake. 6-NBDG can be used as a fluorescent probe for detecting macrophage-rich atherosclerotic plaques.

Lubabegron is a potent modulator of β-adrenergic receptor (β-AR). Lubabegron demonstrates antagonistic behavior at the β₁ and β ₂ receptor subtypes and agonistic behavior at the β ₃ receptor subtype in cattle. Lubabegron reduces NH₃ gas emissions from an animal or its waste. Lubabegron is available as an animal supplement.