1223771-84-3
1223771-84-3
Chemical Structure
S9-A13
- CAS No.: 1223771-84-3
- Formula:C20H18ClN3O2S
- Molecular Weight:399.89
InChIKey: DVGLTSTVSHOWJF-UHFFFAOYSA-N
SMILES: O=C1NC2=C(C(C1)C(C3=CC=C(C)S3)=O)C(C)=NN2C4=CC=C(C)C(Cl)=C4
Biological Activity: S9-A13 is a potent and selective inhibitor SLC26A9, with the IC50 of 90.9 nM, without inhibiting other members of the SLC26 family such as SLC26A3, SLC26A4, and SLC26A6. S9-A13 can inhibits SLC26A9 Cl- currents in cells that lack expression of CFTR[1].
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S9-A13 | S9-A13 is a potent and selective inhibitor SLC26A9, with the IC50 of 90.9 nM, without inhibiting other members of the SLC26 family such as SLC26A3, SLC26A4, and SLC26A6. S9-A13 can inhibits SLC26A9 Cl- currents in cells that lack expression of CFTR. | |||||||||||||||||||||
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References
Keywords
