122341-56-4
Chemical Structure
AMPPD
Synonym(s): Lumi-Phos Plus; Lumigen PPD; PPD
- CAS No.: 122341-56-4
- Formula:C18H23O7P
- Molecular Weight:382.34
IUPAC Name: 3-(4'-methoxyspiro[adamantane-2,3'-[1,2]dioxetan]-4'-yl)phenyl dihydrogen phosphate
InChIKey: XYIPYISRNJUPBA-UHFFFAOYSA-N
SMILES: COC1(C2=CC(OP(O)(O)=O)=CC=C2)C3(C(C4)CC5CC4CC3C5)OO1
Biological Activity: AMPPD (Lumi-Phos Plus; Lumigen PPD) is a chemiluminescent substrate for alkaline phosphatase (APase). AMPPD is hydrolyzed by APase to generate an unstable dioxetane intermediate, and the intermediate releases a chemiluminescent signal when it decomposes. The luminescent signal of AMPPD can be detected by highly sensitive equipment, thereby achieving quantitative analysis of the target molecule. AMPPD can be used in ultrasensitive enzyme-linked immunosorbent assays (such as quantitative detection of human tissue kininogen), chemiluminescent detection of proteins and nucleic acids, and other fields[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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AMPPD | 98.29% | AMPPD (Lumi-Phos Plus; Lumigen PPD) is a chemiluminescent substrate for alkaline phosphatase (APase). AMPPD is hydrolyzed by APase to generate an unstable dioxetane intermediate, and the intermediate releases a chemiluminescent signal when it decomposes. The luminescent signal of AMPPD can be detected by highly sensitive equipment, thereby achieving quantitative analysis of the target molecule. AMPPD can be used in ultrasensitive enzyme-linked immunosorbent assays (such as quantitative detection of human tissue kininogen), chemiluminescent detection of proteins and nucleic acids, and other fields. | ||||||||||||||||||||
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- [1]. Legris F, et al. An ultrasensitive chemiluminoenzyme immunoassay for the quantification of human tissue kininogens: application to synovial membrane and cartilage. J Immunol Methods. 1994 Jan 12;168(1):111-21. [Content Brief]
- [2]. Green MR, et al. Preparation of Labeled DNA, RNA, and Oligonucleotide Probes. Cold Spring Harb Protoc. 2022 Jan 4;2022(1). [Content Brief]
Keywords
