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Axomadol (EN3324) is a centrally active analgesic agent with opioid agonistic properties and inhibitory effects on the reuptake of monoamines.

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Axomadol Chemical Structure

Axomadol Chemical Structure

CAS No. : 187219-99-4

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10 mg USD 1240 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

Axomadol (EN3324) is a centrally active analgesic agent with opioid agonistic properties and inhibitory effects on the reuptake of monoamines[1].

Clinical Trial
Molecular Weight

279.37

Formula

C16H25NO3
CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

O[C@@]1(C2=CC=CC(OC)=C2)C[C@@H](O)CC[C@H]1CN(C)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (357.95 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.5795 mL 17.8974 mL 35.7948 mL
5 mM 0.7159 mL 3.5795 mL 7.1590 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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C2

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V2

In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.5795 mL 17.8974 mL 35.7948 mL 89.4871 mL
5 mM 0.7159 mL 3.5795 mL 7.1590 mL 17.8974 mL
10 mM 0.3579 mL 1.7897 mL 3.5795 mL 8.9487 mL
15 mM 0.2386 mL 1.1932 mL 2.3863 mL 5.9658 mL
20 mM 0.1790 mL 0.8949 mL 1.7897 mL 4.4744 mL
25 mM 0.1432 mL 0.7159 mL 1.4318 mL 3.5795 mL
30 mM 0.1193 mL 0.5966 mL 1.1932 mL 2.9829 mL
40 mM 0.0895 mL 0.4474 mL 0.8949 mL 2.2372 mL
50 mM 0.0716 mL 0.3579 mL 0.7159 mL 1.7897 mL
60 mM 0.0597 mL 0.2983 mL 0.5966 mL 1.4915 mL
80 mM 0.0447 mL 0.2237 mL 0.4474 mL 1.1186 mL
100 mM 0.0358 mL 0.1790 mL 0.3579 mL 0.8949 mL
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Axomadol Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Axomadol187219-99-4EN3324EN 3324EN-3324Othersopioidanalgesicmonoaminesnoradrenalineserotonin5-hydroxytrypyamine5-HTInhibitorinhibitorinhibit

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