1. GPCR/G Protein
    Neuronal Signaling
  2. Dopamine Receptor
  3. A-77636 hydrochloride

A-77636 hydrochloride 

Cat. No.: HY-103416 Purity: ≥98.0%
Handling Instructions

A-77636 hydrochloride is a potent, orally active, selective and long acting dopamine D1 receptor agonist (pKi=7.40; Ki=39.8 nM) with antiparkinsonian activity. A-77636 hydrochloride is functionally inactive at dopamine D2 receptor.

For research use only. We do not sell to patients.

A-77636 hydrochloride Chemical Structure

A-77636 hydrochloride Chemical Structure

CAS No. : 145307-34-2

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5 mg USD 590 In-stock
Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

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Description

A-77636 hydrochloride is a potent, orally active, selective and long acting dopamine D1 receptor agonist (pKi=7.40; Ki=39.8 nM) with antiparkinsonian activity. A-77636 hydrochloride is functionally inactive at dopamine D2 receptor[1][2].

In Vivo

A-77636 (0.1-1 mg/kg) exerts a suppressant effect on food intake, due principally to a reduction in meal size and duration[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male hooded rat[1]
Dosage: 0.1, 0.3 and 1.0 mg/kg
Administration: S.c.
Result: Exerted a suppressant effect on food intake, due principally to a reduction in meal size and duration.
Molecular Weight

365.89

Formula

C₂₀H₂₈ClNO₃

CAS No.
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

References

Purity: ≥98.0%

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Product Name:
A-77636 hydrochloride
Cat. No.:
HY-103416
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