Drug Intermediate
Drug Iintermediate
Drug intermediates are used as raw materials for the production of bulk drugs, or they can refer to a material produced during synthesis of an API that must undergo further molecular change or processing before it becomes an API. Drug intermediates are hygienically formulated using high grade raw materials and they are used in the pharmaceutical and cosmetic industry[1][2].
References:
- [1]. Ma HC, et al. Homochiral Covalent Organic Framework for Catalytic Asymmetric Synthesis of a Drug Intermediate. J Am Chem Soc. 2020 Jul 22;142(29):12574-12578. [Content Brief]
- [2]. Ramachary D B, et al. Development of pharmaceutical drugs, drug intermediates and ingredients by using direct organo‐click reactions[J]. 2008.
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Drug Intermediate Related Products (4608)
Related Products (4608)
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Tropinone
0 ImagesTropinone is an organic synthesis intermediate and a skeleton for constructing derivatives containing thiazole rings and other structures. Tropinone derivatives have anticancer activities such as inducing tumor cell apoptosis and inhibiting tyrosinase activity, and can be used in research such as anticancer drug development and tyrosinase inhibitor design.
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Methyl β-D-glucopyranoside
0 ImagesMethyl β-D-glucopyranoside (Methyl β-D-glucoside) is a model glycosyl acceptor for enzymatic glycosylation reactions. Methyl β-D-glucopyranoside participates in glycoside synthesis and can react with acyl donors such as caffeic acid esters under the catalysis of specific enzymes (such as Lipozyme TL IM) to achieve acylation modification. Methyl β-D-glucopyranoside can generate biologically active derivatives (such as 6-O-caffeoyl glucoside). Methyl β-D-glucopyranoside can be used in organic synthesis and biocatalysis research, especially the efficient enzymatic preparation of medicinal glycosides (such as Robustaside B (HY-N2720), 6-O-caffeoyl salidroside).
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α-Truxillic acid
0 Imagesα-Truxillic acid is form by the dimerization of two molecules of α-trans-cinnamic acid, with anti-inflammatory activities. α-Truxillic acid has no analgesic activity, but its derivatives bound to camphor fragments exhibit significant activity in the peripheral analgesic model (writhing test).
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Doxepin
0 ImagesDoxepin is an orally active, blood-brain barrier penetrant tricyclic antidepressant with multiple activities including hypnosis, sedation, analgesia and vasodilation. Doxepin enhances the expression of PSD-95 and synapsin 1 via the PI3K/AKT/mTOR signaling pathway, and is metabolized to Desmethyldoxepin in vivo. Doxepin can be used in research related to various diseases such as depression, anxiety, obesity and atopic dermatitis.
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2,5-Difluorophenylboronic acid
0 Images2,5-Difluorophenylboronic acid is a phenylboronic acid substituted with 2,5-difluorine groups. 2,5-Difluorophenylboronic acid serves as an organic synthesis intermediate belonging to the fluorinated phenylboronic acid class.
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FR179642
0 ImagesFR179642 is a key intermediate in the synthesis of the echinocandin antifungal Micafungin. FR179642 is the cyclic peptide nucleus of the echinocandin-like antifungal lipopeptide FR901379.
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Diethyl benzylmalonate
0 ImagesDiethyl benzylmalonate is a drug intermediate that can be used for the synthesis of central inhibitory agents.
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Poly(D,L-lactide-co-glycolide)
0 ImagesCat. No.: HY-W723152CAS No.: 26780-50-7Poly(D,L-lactide-co-glycolide) is a biodegradable polymer copolymer. Poly(D,L-lactide-co-glycolide) undergoes degradation through ester bond hydrolysis into lactic acid and glycolic acid. These two products can be naturally eliminated through metabolism in the body (such as the tricarboxylic acid cycle), without the risk of long-term accumulation. Poly(D,L-lactide-co-glycolide) can be used in medical sutures, implants, and drug delivery systems.
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2-Cyanoethylhydrazine
0 ImagesCat. No.: HY-W001874CAS No.: 353-07-1Synonyms: 3-Hydrazinylpropanenitrile2-Cyanoethylhydrazine (3-Hydrazinylpropanenitrile) is a drug synthesis intermediate that can be used to synthesize an antagonist of opioid receptor-like 1 (ORL1).
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4-Methylbiphenyl
0 ImagesSynonyms: 4-Phenyltoluene4-Methylbiphenyl (4-Phenyltoluene) is an organic compound. 4-Methylbiphenyl has excellent chemical stability and antioxidant properties, and is widely used in industry. 4-Methylbiphenyl can serve as a solvent, coating additive, plastic additive and dye intermediate.
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Fmoc-D-allo-Thr-OH
0 ImagesCat. No.: HY-P4613CAS No.: 130674-54-3Fmoc-D-allo-Thr-OH is a derivative of D-allothreonine (HY-W001959), which is commonly used as a building block in solid-phase peptide synthesis (SPPS).
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2,3-Dihydro-7-azaindole
0 ImagesSynonyms: 7-Azaindoline2,3-Dihydro-7-azaindole (7-Azaindoline) is a cyclic secondary amine substrate with a fused aromatic ring, which serves as a substrate for hydrogenation reactions. 2,3-Dihydro-7-azaindole undergoes amidation with methyl pyrazine-2-carboxylate under the catalysis of lipase from Pseudomonas stutzeri. 2,3-Dihydro-7-azaindole is often used as an intermediate in organic synthesis, for example, in the preparation of indole compounds.
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3,4-Difluoronitrobenzene
0 Images3,4-Difluoronitrobenzene is a drug intermediate that can be used for the synthesis of oxazolidone antibiotics.
