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  3. 4-Thiazolecarboxylic acid

4-Thiazolecarboxylic acid (Compound 1e) is an intermediate. 4-Thiazolecarboxylic acid can be used in the synthesis of MGL-IN-2 (HY-177534). MGL-IN-2 inhibits wild-type MGL enzyme activity with an IC50 of 0.0121 μM. 4-Thiazolecarboxylic acid can be used in the research of metabolic diseases.

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4-Thiazolecarboxylic acid

4-Thiazolecarboxylic acid 화학구조

CAS No. : 3973-08-8

사이즈 가격 재고 수량
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
해외재고보유
Solution
10 mM * 1 mL in DMSO 해외재고보유
Solid
10 g 해외재고보유
25 g 해외재고보유
50 g   견적 받기  

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

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제품 설명

4-Thiazolecarboxylic acid (Compound 1e) is an intermediate. 4-Thiazolecarboxylic acid can be used in the synthesis of MGL-IN-2 (HY-177534). MGL-IN-2 inhibits wild-type MGL enzyme activity with an IC50 of 0.0121 μM. 4-Thiazolecarboxylic acid can be used in the research of metabolic diseases[1].

분자량

129.14

화학식

C4H3NO2S

CAS No.
Appearance

Solid

Color

Off-white to light brown

SMILES

O=C(O)C1=CSC=N1

선적

Room temperature in continental US; may vary elsewhere.

보관
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
용액&용해도
In Vitro: 

DMSO : 100 mg/mL (774.35 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 7.7435 mL 38.7177 mL 77.4353 mL
5 mM 1.5487 mL 7.7435 mL 15.4871 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • 몰농도 계산기

  • 농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
순도&문서

Purity: 99.97%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 7.7435 mL 38.7177 mL 77.4353 mL 193.5884 mL
5 mM 1.5487 mL 7.7435 mL 15.4871 mL 38.7177 mL
10 mM 0.7744 mL 3.8718 mL 7.7435 mL 19.3588 mL
15 mM 0.5162 mL 2.5812 mL 5.1624 mL 12.9059 mL
20 mM 0.3872 mL 1.9359 mL 3.8718 mL 9.6794 mL
25 mM 0.3097 mL 1.5487 mL 3.0974 mL 7.7435 mL
30 mM 0.2581 mL 1.2906 mL 2.5812 mL 6.4529 mL
40 mM 0.1936 mL 0.9679 mL 1.9359 mL 4.8397 mL
50 mM 0.1549 mL 0.7744 mL 1.5487 mL 3.8718 mL
60 mM 0.1291 mL 0.6453 mL 1.2906 mL 3.2265 mL
80 mM 0.0968 mL 0.4840 mL 0.9679 mL 2.4199 mL
100 mM 0.0774 mL 0.3872 mL 0.7744 mL 1.9359 mL
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

상품명:
4-Thiazolecarboxylic acid
Cat. No.:
HY-59320
수량:
MCE Japan Authorized Agent: