490-20-0
490-20-0
Chemical Structure
α-Truxillic acid
- CAS No.: 490-20-0
- Formula:C18H16O4
- Molecular Weight:296.32
IUPAC Name: (1R,2R,3S,4S)-2,4-diphenylcyclobutane-1,3-dicarboxylic acid
InChIKey: QWFRRFLKWRIKSZ-BIAGXBKMSA-N
SMILES: OC([C@H]1[C@@H]([C@@H]([C@H]1C2=CC=CC=C2)C(O)=O)C3=CC=CC=C3)=O
Biological Activity: α-Truxillic acid is form by the dimerization of two molecules of α-trans-cinnamic acid, with anti-inflammatory activities. α-Truxillic acid has no analgesic activity, but its derivatives bound to camphor fragments exhibit significant activity in the peripheral analgesic model (writhing test)[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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α-Truxillic acid | 99.93% | α-Truxillic acid is form by the dimerization of two molecules of α-trans-cinnamic acid, with anti-inflammatory activities. α-Truxillic acid has no analgesic activity, but its derivatives bound to camphor fragments exhibit significant activity in the peripheral analgesic model (writhing test). | ||||||||||||||||||||
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References
- [1]. Chi YM, et al. Antinociceptive activities of alpha-truxillic acid and beta-truxinic acid derivatives. Biol Pharm Bull. 2006 Mar;29(3):580-4. [Content Brief]
- [2]. Sokolova A, et al. Synthesis and analgesic activity of new α-truxillic acid derivatives with monoterpenoid fragments[J]. Medicinal Chemistry Research, 2016, 25(8): 1608-1615.
