Drug Intermediate
Drug Iintermediate
Drug intermediates are used as raw materials for the production of bulk drugs, or they can refer to a material produced during synthesis of an API that must undergo further molecular change or processing before it becomes an API. Drug intermediates are hygienically formulated using high grade raw materials and they are used in the pharmaceutical and cosmetic industry[1][2].
References:
- [1]. Ma HC, et al. Homochiral Covalent Organic Framework for Catalytic Asymmetric Synthesis of a Drug Intermediate. J Am Chem Soc. 2020 Jul 22;142(29):12574-12578. [Content Brief]
- [2]. Ramachary D B, et al. Development of pharmaceutical drugs, drug intermediates and ingredients by using direct organo‐click reactions[J]. 2008.
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Drug Intermediate Related Products (4595)
Related Products (4595)
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L-Fucitol
0 ImagesSynonyms: 1-Deoxy-D-galactitolL-Fucitol (1-Deoxy-D-galactitol) is a type of sugar alcohol that can be found in Nutmeg. L-Fucitol can be used as a raw material to prepare L-Fuco-4-ketose for pharmaceutical purposes.
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24(R)-Hydroxycholesterol
0 ImagesSynonyms: 24R-OHC; 24R-HC; 24(R)-Cerebrosterol24(R)-Hydroxycholesterol (24R-OHC) is a key intermediate of Tacalcitol (HY-32337).
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Fmoc-PNA-G(Bhoc)-OH
0 ImagesCat. No.: HY-W025936CAS No.: 186046-83-3Fmoc‑PNA‑G (Bhoc)‑OH is a guanine-containing peptide nucleic acid monomer, in which both Bhoc on the nucleobase and Fmoc on the backbone serve as protecting groups. Fmoc‑PNA‑G (Bhoc)‑OH is applicable for the synthesis of peptide nucleic acids.
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DL-Cystathionine-d4
0 ImagesDL-Cystathionine-d4 is the deuterium labeled DL-Cystathionine (HY-W009749A). DL-Cystathionine is a mixture of 4 isomers of cystathionine and allocystathionine. DL-Cystathionine also is an intermediate in the biosynthesis of amino acid cysteine. DL-Cystathionine serves as a standard for quantifying tissue cystathionine.
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GGFG-Exatecan TFA
0 ImagesCat. No.: HY-128994ACAS No.: 223537-11-9GGFG-Exatecan TFA is a synthetic intermediate for drug-linker conjugates used in antibody-drug conjugates (ADCs). GGFG-Exatecan TFA consists of a glycyl-glycyl-phenylalanyl-glycine (GGFG) tetrapeptide linker and a DNA topoisomerase I inhibitor Exatecan (HY-13631). GGFG-Exatecan TFA can be used for the study of cancer.
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Ganoderic acid I
0 ImagesGanoderic acid I is a lanostane-type triterpenoid compound present in Ganoderma lucidum.
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2,2-Dihydroxy-1-phenylethan-1-one
0 Images2,2-Dihydroxy-1-phenylethan-1-one (Phenylglyoxal hydrate) is a phenylglyoxal-based, antioxidant drug synthesis intermediate. 2,2-Dihydroxy-1-phenylethan-1-one serves as a starting material for the synthesis of aromatic amines or aliphatic amines. It can be used to synthesize polysubstituted pyrrolo[3,2-c]pyridin-4-one derivatives, and also acts as a key structural unit in the microwave-assisted cascade synthesis of substituted 2-methyl-7-aryl-6H-thiazoloindole compounds.
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H-Val-Val-OH
0 ImagesH-Val-Val-OH (Val-Val) is a stereochemistry-dependent substrate and inhibitor of apical oligopeptide transporters. H-Val-Val-OH undergoes apical intracellular accumulation in human intestinal cells via carrier-mediated transport, and inhibits the uptake of Cephalexin (HY-B0200) through interaction with transporters. Substitution of L-valine with D-valine in H-Val-Val-OH abolishes its binding ability to apical oligopeptide transporters.
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H-D-cis-Hyp-OH
0 ImagesH-D-cis-Hyp-OH is a proline derivative and also a substrate of cis-4-hydroxy-D-proline dehydrogenase from Sinorhizobium meliloti. H-D-cis-Hyp-OH serves as a starting material for the synthesis of conformationally constrained pyrrolidine PNA adenine monomers.
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4-Bromo-2-methoxyphenol
0 ImagesSynonyms: 4-Bromoguaiacol4-Bromo-2-methoxyphenol (4-Bromoguaiacol) is a phenolic compound. 4-Bromo-2-methoxyphenol serves as a synthetic intermediate for the preparation of PT70. 4-Bromo-2-methoxyphenol acts as a precursor for generating masked ortho-benzoquinone (MOB) 6.
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Procysteine
0 ImagesSynonyms: Oxothiazolidinecarboxylic acidProcysteine, an antioxidant, is a proagent of cysteine that is inert until metabolized to cysteine intracellulary, thus stimulating glutathione synthesis.
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Leflunomide impurity 7
0 ImagesCat. No.: HY-78861CAS No.: 24522-30-3Leflunomide impurity 7 is an impurity of Leflunomide.
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1-Phenyl-1-propanol
0 Images1-Phenyl-1-propanol is used as a chiral building block and synthetic intermediate in the pharmaceutical industries. 1-Phenyl-1-propanol is an intermediate of anti-depressant agent Fluoxetine (HY-B0102).
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Benzgalantamine
0 ImagesSynonyms: GLN-1062Benzgalantamine (GLN-1062) is a pro-agent of galantamine, used for the treatment for Alzheimer’s disease.
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Cyanosafracin B
0 ImagesCat. No.: HY-137787CAS No.: 96996-50-8Cyanosafracin B is a starting material for synthesis of Ecteinascidin ET-743 and Phthalascidin Pt-650.
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3,5-Dihydroxyacetophenone
0 Images3,5-Dihydroxyacetophenone is a drug intermediate that can be used in the synthesis of the active stilbene dimer dehydro-δ-viniferin.
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Psoralenoside
0 ImagesPsoralenoside is an orally active benzofuran glycoside. Psoralenoside is isolated from the fruits of Psoralea corylifolia. As a metabolite precursor, Psoralenoside undergoes deglycosylation by intestinal flora to form Psoralen (HY-N0053). Psoralenoside is applicable to research related to cancer and bacterial infections.
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AMG 118 (Immobilized cephalosporin C acylase)
0 ImagesCat. No.: HY-E70137AMG 118 Immobilized cephalosporin C acylase is an enzyme that catalyzes in immobilized form and is generally used in industrial catalytic production of the important pharmaceutical intermediate 7-aminocephalosporanic acid (7-ACA). It contains CPC acylase, a highly specialized beta-lactam acylase or peptidase that cleaves the amide bonds between beta-lactams.
