AF10 Antibody (YA2017)

製品番号: HY-P82272: データシート User Guide for Antibodies
FAQs
Technical Support

AF10 Antibody (YA2017) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to AF10.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

容量	価格（税別）	在庫状況	数量
20 μL	$146	Get quote 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
50 μL	$222	Get quote 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
100 μL	$360	Get quote 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
250 μL		お問い合わせ

Synthetic products have potential research and development risk.

or バルクお問い合わせ

* アイテムを追加する前、数量をご選択ください

おすすめ:

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
説明

製品説明

AF10 Antibody (YA2017) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to AF10.

Host

Rabbit

Clonality

Recombinant, Monoclonal

分子量

Predicted band size: 113 kDa;

Observed band size: 140 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human

SwissProt ID

P55197

Gene ID

8028 [NCBI]

Immunogen

Recombinant protein of human AF10 aa788-1050.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:1000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:50-1:100

Sensitivity	Endogenous	純度	Affinity Purified
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

輸送条件

Shipping with blue ice.

Background

Function：Probably involved in transcriptional regulation. In vitro or as fusion protein with KMT2A/MLL1 has transactivation activity. Binds to cruciform DNA. In cells, binding to unmodified histone H3 regulates DOT1L functions including histone H3 'Lys-79' dimethylation (H3K79me2) and gene activation (PubMed:26439302)

Subcellular Localization：Nucleus

Expression：
Tissue_specificity:Expressed abundantly in testis

Isoforms & Post-Translational Modification：P55197 has 4 isomers: P55197-4: 113320 Da (predicted); P55197-1: 109026 Da (predicted); P55197-2: 13851 Da (predicted); P55197-3: 20047 Da (predicted).

Subunit：Self-associates. Interacts with FSTL3 isoform 2; the interaction enhances MLLT10 in vitro transcriptional activity and self-association. Interacts with YEATS4.

Database

Entrez Gene: 8028 Human

SwissProt: P55197 Human

OMIM: 602409 Human

Research Field

Epigenetics and Nuclear Signaling

Synonyms

MLLT10; AF10; Protein AF-10; ALL1-fused gene from chromosome 10 protein

ドキュメンテーション

User Guide for Antibodies (1077 KB)