Calsequestrin 2 Antibody (YA6527)

Cat. No.: HY-P86834: Data Sheet User Guide for Antibodies
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Calsequestrin 2 Antibody (YA6527) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Calsequestrin 2.

For research use only. We do not sell to patients.

Size	Price	Stock
20 μL		Ask For Quote & Lead Time
50 μL		Ask For Quote & Lead Time
100 μL		Ask For Quote & Lead Time

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

Calsequestrin 2 Antibody (YA6527) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Calsequestrin 2.

Host

Rabbit

Clonality

Recombinant,Monoclonal

Molecular Weight

Predicted band size: 46 kDa;

Observed band size: 55 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse, Rat

SwissProt ID

O14958

Gene ID

845 [NCBI]

Immunogen

Recombinant protein within human Calsequestrin 2 aa 1-399 / 399.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:2000-1:10000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:1000
IF-Tissue IF-Tissue: Immunofluorescence-Tissue	1:500

Purity	affinity purified.	Conjugation	Non-conjugated
Modification	Unmodified	Isotype	IgG

Appearance

Liquid

Formulation

Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle. Calcium ions are bound by clusters of acidic residues at the protein surface, especially at the interface between subunits. Can bind around 60 Ca(2+) ions. Regulates the release of lumenal Ca(2+) via the calcium release channel RYR2; this plays an important role in triggering muscle contraction. Plays a role in excitation-contraction coupling in the heart and in regulating the rate of heart beats

Subcellular Localization：Sarcoplasmic reticulum lumen

Isoforms & Post-Translational Modification：O14958 has 2 isomers: O14958-1: 46436 Da (predicted); O14958-2: 38269 Da (predicted).
Phosphorylation in the C-terminus, probably by CK2, moderately increases calcium buffering capacity;N-glycosylated

Subunit：Monomer, homodimer and homooligomer

Synonyms

AA033488 antibody; AW146219 antibody; Calsequestrin 2 (cardiac muscle) antibody; Calsequestrin 2 fast twitch cardiac muscle antibody; Calsequestrin antibody; Calsequestrin cardiac muscle isoform antibody; Calsequestrin fast twitch cardiac muscle antibody; Calsequestrin-2 antibody; Calsequestrin2 antibody; cardCSQ antibody; AA033488 antibody; AW146219 antibody; Calsequestrin 2 (cardiac muscle) antibody; Calsequestrin 2 fast twitch cardiac muscle antibody; Calsequestrin antibody; Calsequestrin cardiac muscle isoform antibody; Calsequestrin fast twitch cardiac muscle antibody; Calsequestrin-2 antibody; Calsequestrin2 antibody; cardCSQ antibody; Cardiac calsequestrin 2 antibody; cardiac muscle isoform antibody; CASQ 2 antibody; CASQ2 antibody; CASQ2_HUMAN antibody; cCSQ antibody; ESTM52 antibody; FLJ26321 antibody; FLJ93514 antibody; PDIB2 antibody;

Documentation

User Guide for Antibodies (1077 KB)