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  4. IL-10 Antibody

IL-10 Antibody

Cat. No.: HY-P81113
COA User Guide for Antibodies

IL-10 Antibody is an unconjugated, approximately 18 kDa, rabbit-derived, anti-IL-10 monoclonal antibody. IL-10 Antibody can be used for: WB, ICC, FC expriments in human background without labeling.

For research use only. We do not sell to patients.

Size Price Stock Quantity
10 μL $70 In-stock
50 μL $185 In-stock
100 μL $300 In-stock
250 μL   Get quote  

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Top Publications Citing Use of Products
  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

IL-10 Antibody is an unconjugated, approximately 18 kDa, rabbit-derived, anti-IL-10 monoclonal antibody. IL-10 Antibody can be used for: WB, ICC, FC expriments in human background without labeling.

Background

The protein encoded by The related gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. The cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. The cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of The cytokine as an essential immunoregulator in the intestinal tract. Mutations in The related gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.

Gene ID

3586

Synonyms
Interleukin-10 precursor; Cytokine synthesis inhibitory factor; CSIF; Cytokine Synthesis Inhibitory Factor; IL 10; IL10A; Interleukin 10; Interleukin10; MGC126450; MGC126451; TGIF; IL10_HUMAN. 白介素10
Molecular Weight

Predicted band size: 18kDa

Purity

affinity purified

Subcellular Location

Secreted.

Conjugation

Non-conjugated

Modification

Unmodified

Product Categories

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Clonality

Monoclonal

Host

Rabbit

Reactivity

Human

SwissProt ID

P22301

Dilution Ratio

WB: 1/500-1/1000; IF: 1/50-1/200; FC: 1/50-1/100

Application

WB, ICC/IF, FC

Appearance

Liquid

Formulation

Supplied in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Isotype

IgG

Sensitivity

Endogenous

Immunogen

A synthesized peptide derived from human IL10.

Documentation
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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IL-10 Antibody
Cat. No.:
HY-P81113
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