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PE-conjugated CD45 Antibody (2D1)

(Synonyms: CD45,CD45-PE,2D1)

PE-conjugated CD45 Antibody (2D1) is a Mouse-derived and PE conjugated monoclonal antibody, targeting to CD45.

For research use only. We do not sell to patients.
  • Host:

    Mouse

  • Isotype:

    Mouse IgG1,κ

  • Application:

    FC

  • Reactivity :

    Human

  • Formulation:

    Supplied in PBS (pH 7.2) containing 0.1% Proclin300 and protein stabilizer.

  • Conjugation:
    PE
  • PE-conjugated CD45 Antibody (2D1) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Use of MCE Products

Applications

Application
FC Info
FC: Flow Cytometry
Dilution Ratio 5 ul per 106 cells in a 100 µl suspension

Product Details

Description

PE-conjugated CD45 Antibody (2D1) is a Mouse-derived and PE conjugated monoclonal antibody, targeting to CD45.

  • Host Mouse
  • Clonality Monoclonal
  • Species Reactivity
    Human
Conjugation

PE

Modification

Unmodified

Isotype

Mouse IgG1,κ

Product Properties

  • Appearance

    Solution

  • Formulation

    Supplied in PBS (pH 7.2) containing 0.1% Proclin300 and protein stabilizer.

  • Storage & Stability

    Stored at 2-8°C for 1 year, protect from light, do not freeze.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    CD45 (PTPRC/LCA) is a receptor-type protein tyrosine phosphatase common to all white blood cells and is the most classic pan-marker of immune cells. CD45 can be used to label hematopoietic cells, regulate TCR, BCR, and NK cell activation signals, and control immune cell development, differentiation, and function.

  • Expression


    Tissue_specificity:Isomer 1: Detected in thymocytes. Isomer 2: Detected in thymocytes. Isomer 3: Detected in thymocytes. Isomer 4: Not detected in thymocytes. Isomer 5: Detected in thymocytes. Isomer 6: Not detected in thymocytes. Isomer 7: Detected in thymocytes. Isomer 8: Not detected in thymocytes.

  • Isoforms & Post-Translational Modification

    CD45 has 8 isomers: P08575-3: 147486 Da (predicted); P08575-4: 131130 Da (predicted); P08575-5: 142623 Da (predicted); P08575-6: 142898 Da (predicted); P08575-7: 140582 Da (predicted); P08575-8: 138034 Da (predicted); P08575-9: 135719 Da (predicted); P08575-10: 135993 Da (predicted).
    Heavily N- and O-glycosylated

  • Subunit

    Binds GANAB and PRKCSH (By similarity). Interacts with SKAP1. Interacts with DPP4; the interaction is enhanced in an interleukin-12-dependent manner in activated lymphocytes

  • Synonyms

    CD45,CD45-PE,2D1

PE-conjugated CD45 Antibody (2D1) Related Classifications

MOQ
Minimum order quantity
100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
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  • PE-conjugated CD45 Antibody (2D1) Product Image