PEG3 Antibody (YA8688)
(Synonyms: PW1; ZKSCAN22; ZNF904; ZSCAN24)PEG3 Antibody (YA8688) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PEG3.
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Host:
Mouse
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Isotype:
IgG1
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Application:
IHC-P
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Reactivity :
Human
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
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Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|
| Dilution Ratio | 1:150-500 |
Product Details
PEG3 Antibody (YA8688) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PEG3.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
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Calculated Molecular Weight Predicted band size: 180.6 kDa
Human recombinant protein fragment corresponding to amino acids 1-364 of human PEG3 produced in E.coli.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
PEG3 induces apoptosis in cooperation with SIAH1A. Acts as a mediator between p53/TP53 and BAX in a neuronal death pathway that is activated by DNA damage. Acts synergistically with TRAF2 and inhibits TNF induced apoptosis through activation of NF-kappa-B. Possesses a tumor suppressing activity in glioma cells
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Subcellular Localization
Nucleus,Cytoplasm
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Expression
Tissue_Specificity: Brain, glial cells, astrocytes, embryo, placenta, testis, ovary and uterus. In the placenta it is found in the layer of villous cytotrophoblast cells while in the ovary it is found in the cells of the ovarian stroma including the thecal layers around the follicles. Expression is highly repressed in glioma cell lines -
Isoforms & Post-Translational Modification
Q9GZU2 has four isomers: Q9GZU2-1: 180827 Da (predicted); Q9GZU2-2: 165957 Da (predicted); Q9GZU2-3: 60547 Da (predicted); Q9GZU2-4: 166071 Da (predicted).
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Subunit
Homodimer
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SwissProt ID
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Synonyms
PW1; ZKSCAN22; ZNF904; ZSCAN24
Documentation
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