PITPNB Antibody (YA8216)
(Synonyms: PI-TP-beta; PtdInsTP; VIB1B)PITPNB Antibody (YA8216) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PITPNB.
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Host:
Mouse
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Isotype:
IgG1
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Application:
IHC-P
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Reactivity :
Human, Mouse, Rat
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
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Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|
| Dilution Ratio | 1:150-500 |
Product Details
PITPNB Antibody (YA8216) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PITPNB.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman, Mouse, Rat
Full length human recombinant protein of human PITPNB produced in E.coli.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
PITPNB catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes. Also catalyzes the transfer of sphingomyelin. Required for COPI-mediated retrograde transport from the Golgi to the endoplasmic reticulum; phosphatidylinositol and phosphatidylcholine transfer activity is essential for this function[1][2][3].
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Subcellular Localization
Golgi apparatus,Golgi apparatus membrane,Endoplasmic reticulum membrane
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Expression
Tissue_Specificity: Widely expressed in various tissues including brain -
Isoforms & Post-Translational Modification
P48739 has three isomers: P48739-1: 31540 Da (predicted); P48739-2: 31638 Da (predicted); P48739-3: 31700 Da (predicted).
Constitutive phosphorylation of Ser-262 has no effect on phospholipid transfer activity but is required for Golgi targeting -
SwissProt ID
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Synonyms
PI-TP-beta; PtdInsTP; VIB1B
Documentation
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