PTBP3 Antibody (YA8355)
(Synonyms: ROD1)PTBP3 Antibody (YA8355) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to PTBP3.
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Host:
Mouse
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Isotype:
IgG
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Application:
WB, IHC-P
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Reactivity :
Human, Mouse, Rat
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|---|
| Dilution Ratio | 1:1000-4000 | 1:500-800 |
Product Details
PTBP3 Antibody (YA8355) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to PTBP3.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman, Mouse, Rat
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Calculated Molecular Weight Predicted band size: 59.5 kDa
Human recombinant protein fragment corresponding to amino acids 300-552 of human PTBP3 produced in E.coli.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
PTBP3 is a RNA-binding protein that mediates pre-mRNA alternative splicing regulation. Plays a role in the regulation of cell proliferation, differentiation and migration. Positive regulator of EPO-dependent erythropoiesis. Participates in cell differentiation regulation by repressing tissue-specific exons. Promotes FAS exon 6 skipping. Binds RNA, preferentially to both poly(G) and poly(U)
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Expression
Tissue_Specificity: Expressed in several hematopoietic cell lines examined -
Isoforms & Post-Translational Modification
O95758 has 7 isomers: O95758-3: 59690 Da (predicted); O95758-1: 56502 Da (predicted); O95758-2: 59112 Da (predicted); O95758-4: 60417 Da (predicted); O95758-5: 60009 Da (predicted); O95758-6: 56821 Da (predicted); O95758-7: 49540 Da (predicted).
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Subunit
Interacts with THBS4 (via the acidic amphipathic C-terminus)
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SwissProt ID
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Synonyms
ROD1
Documentation
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