SEC11A Antibody (YA8824)
(Synonyms: 1810012E07Rik; SEC11L1; sid2895; SPC18; SPCS4A)SEC11A Antibody (YA8824) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to SEC11A.
-
Host:
Mouse
-
Isotype:
IgG2b
-
Application:
IHC-P
-
Reactivity :
Human, Mouse, Rat
-
Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
-
Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
|
|---|---|
| Dilution Ratio | 1:150-500 |
Product Details
SEC11A Antibody (YA8824) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to SEC11A.
-
Host Mouse
-
Clonality Monoclonal
-
Species ReactivityHuman, Mouse, Rat
-
Calculated Molecular Weight Predicted band size: 20.4 kDa
Full length human recombinant protein of human SEC11A produced in E.coli.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG2b
Product Properties
-
Appearance
Liquid
-
Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
-
Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
-
Shipping
Shipping with blue ice.
Background
-
Function
SEC11A is a Catalytic component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. Specifically cleaves N-terminal signal peptides that contain a hydrophobic alpha-helix (h-region) shorter than 18-20 amino acids[1].
-
Subcellular Localization
Endoplasmic reticulum membrane
-
Isoforms & Post-Translational Modification
P67812 has four isomers: P67812-1: 20625 Da (predicted); P67812-2: 17408 Da (predicted); P67812-3: 21454 Da (predicted); P67812-4: 18988 Da (predicted).
-
Subunit
Component of the signal peptidase complex paralog A (SPC-A) composed of a catalytic subunit SEC11A and three accessory subunits SPCS1, SPCS2 and SPCS3 (PubMed:34388369)
-
SwissProt ID
-
Synonyms
1810012E07Rik; SEC11L1; sid2895; SPC18; SPCS4A
Documentation
Powered by Bioz
