SLU7 Antibody (YA8339)
(Synonyms: 9G8; hSlu7)SLU7 Antibody (YA8339) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to SLU7.
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Host:
Mouse
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Isotype:
IgG1
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Application:
IHC-P
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Reactivity :
Human, Mouse, Rat
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
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Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|
| Dilution Ratio | 1:800-1500 |
Product Details
SLU7 Antibody (YA8339) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to SLU7.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman, Mouse, Rat
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Calculated Molecular Weight Predicted band size: 68.2 kDa
Human recombinant protein fragment corresponding to amino acids 1-300 of human SLU7 produced in E.coli.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
SLU7 is required for pre-mRNA splicing as component of the spliceosome. Participates in the second catalytic step of pre-mRNA splicing, when the free hydroxyl group of exon I attacks the 3'-splice site to generate spliced mRNA and the excised lariat intron. Required for holding exon 1 properly in the spliceosome and for correct AG identification when more than one possible AG exists in 3'-splicing site region. May be involved in the activation of proximal AG. Probably also involved in alternative splicing regulation[1][2][3].
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Subcellular Localization
Nucleus,Nucleus speckle,Cytoplasm
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Isoforms & Post-Translational Modification
O95391: 586 amino acids, molecular weight 68387 Da.
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Subunit
Component of pre-catalytic, catalytic and post-catalytic spliceosomes (PubMed:10197984, PubMed:28502770, PubMed:30705154)
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SwissProt ID
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Synonyms
9G8; hSlu7
Documentation
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