WDR74 Antibody (YA8683)
(Synonyms: FLJ10439; FLJ21730)WDR74 Antibody (YA8683) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to WDR74.
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Host:
Mouse
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Isotype:
IgG1
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Application:
IHC-P
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Reactivity :
Human, Dog, Rat, Monkey, Mouse
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
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Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|
| Dilution Ratio | 1:150-500 |
Product Details
WDR74 Antibody (YA8683) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to WDR74.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman, Dog, Rat, Monkey, Mouse
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Calculated Molecular Weight Predicted band size: 42.3 kDa
Human recombinant protein fragment corresponding to amino acids 114-385 of human WDR74 produced in E.coli.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
WDR74 is a Regulatory protein of the MTREX-exosome complex involved in the synthesis of the 60S ribosomal subunit. Participates in an early cleavage of the pre-rRNA processing pathway in cooperation with NVL. Required for blastocyst formation, is necessary for RNA transcription, processing and/or stability during preimplantation development[1][2].
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Subcellular Localization
Nucleus, nucleolus,Nucleus
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Isoforms & Post-Translational Modification
Q6RFH5 has two isomers: Q6RFH5-1: 42441 Da (predicted); Q6RFH5-2: 40208 Da (predicted).
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Subunit
Isoform 1 interacts (through WDR repeats) with NVL; the interaction is independent of RNA or pre-60S ribosome particles
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SwissProt ID
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Synonyms
FLJ10439; FLJ21730
Documentation
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