ZRANB2 Antibody (YA8774)
(Synonyms: ZIS; ZIS1; ZIS2; ZNF265)ZRANB2 Antibody (YA8774) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to ZRANB2.
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Host:
Mouse
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Isotype:
IgG1
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Application:
IHC-P
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Reactivity :
Human
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
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Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|
| Dilution Ratio | 1:2000-2500 |
Product Details
ZRANB2 Antibody (YA8774) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to ZRANB2.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
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Calculated Molecular Weight Predicted band size: 36.1 kDa
Human recombinant protein fragment corresponding to amino acids 95-320 of human ZRANB2 produced in E.coli.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
ZRANB2 is a Splice factor required for alternative splicing of TRA2B/SFRS10 transcripts. Binds to ssRNA containing the consensus sequence 5'-AGGUAA-3'. May interfere with constitutive 5'-splice site selection[1].
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Subcellular Localization
Nucleus
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Isoforms & Post-Translational Modification
O95218 has two isomers: O95218-1: 37404 Da (predicted); O95218-2: 36318 Da (predicted).
Isoform 2 is phosphorylated on Ser-310 upon DNA damage, probably by ATM or ATR -
Subunit
Interacts with the C-terminal half of SNRNP70, the Arg/Ser-rich domain of AKAP17A as well as with U2AF1 and CLK1
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SwissProt ID
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Synonyms
ZIS; ZIS1; ZIS2; ZNF265
Documentation
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