Ppp1r9b - protein phosphatase 1, regulatory subunit 9B Gene

Also Known as SPL; Spn

Species: Mus musculus

Gene Type: protein coding
Gene ID: 217124

Summary

Predicted to enable several functions, including D2 Dopamine Receptor binding activity; enzyme binding activity; and protein C-terminus binding activity. Involved in cellular response to morphine and regulation of Opioid Receptor signaling pathway. Acts upstream of or within several processes, including actin filament organization; calcium-mediated signaling; and dendrite development. Located in cortical actin Cytoskeleton and filopodium. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and immune system. Orthologous to human PPP1R9B (protein Phosphatase 1 regulatory subunit 9B). [provided by Alliance of Genome Resources, Apr 2022]

Ppp1r9b Products (1)

mRNA Protein Name
NM_172261.3 NP_758465.2 neurabin-2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Références Source
enables protein binding IPI
IPI: Inferred from physical interaction
14550532 MGI
Biological Process GO Annotation Evidence Références Source
acts upstream of or within actin filament organization IPI
IPI: Inferred from physical interaction
15996550 MGI
acts upstream of or within calcium-mediated signaling IMP
IMP: Inferred from mutant phenotype
17464283 MGI
involved in cellular response to morphine IMP
IMP: Inferred from mutant phenotype
18439408 MGI
acts upstream of or within dendrite development IMP
IMP: Inferred from mutant phenotype
10922077 MGI
involved in regulation of opioid receptor signaling pathway IMP
IMP: Inferred from mutant phenotype
18439408 MGI
involved in regulation of postsynapse assembly IDA
IDA: Inferred from direct assay
10922077 MGI
involved in regulation of postsynapse assembly IMP
IMP: Inferred from mutant phenotype
10922077 MGI
acts upstream of or within regulation of protein phosphorylation IMP
IMP: Inferred from mutant phenotype
15218143 MGI
Cellular Component GO Annotation Evidence Références Source
located in cortical actin cytoskeleton IDA
IDA: Inferred from direct assay
15996550 MGI
located in filopodium IDA
IDA: Inferred from direct assay
15996550 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

neurabin-2

  • neurabin-II

  • spinophilin

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-RS11006 PPP1R9B Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ppp1r9b NCBI NCBI:84687