NLRP3-IN-85
NLRP3-IN-85 (compound 5d) is a potent NLRP3 inhibitor that targets mitochondria in a ΔΨm-independent manner. NLRP3-IN-85 protects mitochondria from oxidative stress and inflammation damage and suppresses key inflammatory factors (NO, TNF-α, IL-6). NLRP3-IN-85 relives acute lung injury in mice and inhibits paw edema in rats. NLRP3-IN-85 can be used for acute lung injury (ALI) research.
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- Formule: C26H26F3N3O6
- Masse moléculaire:533.50
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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NLRP3 |
IL-6 |
Chemical Information
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Masse moléculaire 533.50
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Formule C26H26F3N3O6
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SMILES
OC1=C(O)C=CC(/C=C(C(NCCNC(C2=CC(C=CC(N(CC)CC)=C3)=C3OC2=O)=O)=O)\C(F)(F)F)=C1
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)