1071-23-4
Chemical Structure
Phosphorylethanolamine
Synonym(s): Monoaminoethyl phosphate; NSC 254167; O-Phosphoethanolamine
- CAS No.: 1071-23-4
- Formula:C2H8NO4P
- Molecular Weight:141.06
IUPAC Name: 2-aminoethyl dihydrogen phosphate
InChIKey: SUHOOTKUPISOBE-UHFFFAOYSA-N
SMILES: NCCOP(O)(O)=O
Biological Activity: Phosphorylethanolamine (Monoaminoethyl phosphate) is a membrane phospholipid and an important precursor of Phosphatidylcholine (HY-B2233B). It is found in most animal tissues and various human extracranial tumors, playing a critical role in membrane integrity, cell division, mitochondrial respiratory function, and more. Studies have shown that changes in the abundance of Phosphorylethanolamine are associated with Alzheimer's disease and Parkinson's disease. Lowering the ratio of Phosphorylethanolamine to Phosphatidylcholine in the liver can improve insulin signaling. Phosphorylethanolamine holds promise for research in the fields of cancer, neurodegenerative disorders, and metabolic diseases[1][2][3][4][5].
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Phosphorylethanolamine | 99.90% | Phosphorylethanolamine (Monoaminoethyl phosphate) is a membrane phospholipid and an important precursor of Phosphatidylcholine (HY-B2233B). It is found in most animal tissues and various human extracranial tumors, playing a critical role in membrane integrity, cell division, mitochondrial respiratory function, and more. Studies have shown that changes in the abundance of Phosphorylethanolamine are associated with Alzheimer's disease and Parkinson's disease. Lowering the ratio of Phosphorylethanolamine to Phosphatidylcholine in the liver can improve insulin signaling. Phosphorylethanolamine holds promise for research in the fields of cancer, neurodegenerative disorders, and metabolic diseases. | ||||||||||||||||||||
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Phosphorylethanolamine (Standard) | 99.93% | Phosphorylethanolamine (Standard) is the analytical standard of Phosphorylethanolamine. This product is intended for research and analytical applications. Phosphorylethanolamine (Monoaminoethyl phosphate) is present in most animal tissues and is also present in various human extracranial tumors. Phosphorylethanolamine is considered as the intermediate product of phospholipid metabolism. Phosphorylethanolamine is essential for the formation and maintenance of the cell membrane. | ||||||||||||||||||||
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Phosphorylethanolamine-d4 | Phosphorylethanolamine-d4 (Monoaminoethyl phosphate-d4; NSC 254167-d4) is a deuterium labeled Phosphorylethanolamine (HY-N5034). Phosphorylethanolamine is an endogenous metabolite. | |||||||||||||||||||||
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- [1]. Kinoshita Y, et al. Phosphorylethanolamine content of human brain tumors. Neurol Med Chir (Tokyo). 1994 Dec;34(12):803-6. [Content Brief]
- [2]. Hui SCN, et al. In vivo spectral editing of phosphorylethanolamine. Magn Reson Med. 2022 Jan;87(1):50-56. [Content Brief]
- [3]. Calzada E,et al. Phosphatidylethanolamine Metabolism in Health and Disease. Int Rev Cell Mol Biol. 2016;321:29-88. doi: 10.1016/bs.ircmb.2015.10.001. [Content Brief]
- [4]. van der Veen JN, et al. A role for phosphatidylcholine and phosphatidylethanolamine in hepatic insulin signaling. FASEB J. 2019 Apr;33(4):5045-5057. [Content Brief]
- [5]. Nesic I, et al. Alterations in phosphatidylethanolamine levels affect the generation of Aβ. Aging Cell. 2012 Feb;11(1):63-72. [Content Brief]
