563-96-2
563-96-2
Chemical Structure
2,2-Dihydroxyacetic acid
- CAS No.: 563-96-2
- Formula:C2H4O4
- Molecular Weight:92.05
IUPAC Name: 2,2-dihydroxyacetic acid
InChIKey: GOCCREQJUBABAL-UHFFFAOYSA-N
SMILES: O=C(C(O)O)O
Biological Activity: 2,2-Dihydroxyacetic acid is an endogenous metabolite, which is the monohydrate of Glyoxylic Acid. 2,2-Dihydroxyacetic acid may participate in the microbial glyoxylate cycle, induce an increase in reactive oxygen species, promote cell differentiation, and modify proteins to form advanced glycation end products (AGEs) (HY-NP165). 2,2-Dihydroxyacetic acid is associated with metabolic diseases such as primary hyperoxaluria[1][2][3][4].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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2,2-Dihydroxyacetic acid | 98.0% | 2,2-Dihydroxyacetic acid is an endogenous metabolite, which is the monohydrate of Glyoxylic Acid. 2,2-Dihydroxyacetic acid may participate in the microbial glyoxylate cycle, induce an increase in reactive oxygen species, promote cell differentiation, and modify proteins to form advanced glycation end products (AGEs) (HY-NP165). 2,2-Dihydroxyacetic acid is associated with metabolic diseases such as primary hyperoxaluria. | ||||||||||||||||||||
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2,2-Dihydroxyacetic acid (Standard) | ≥98% | 2,2-Dihydroxyacetic acid (Standard) is the analytical standard of 2,2-Dihydroxyacetic acid (HY-W019724). This product is intended for research and analytical applications. 2,2-Dihydroxyacetic acid is a key intermediate used in the synthesis of 3-aminocoumarone derivatives, which exhibit significant activity in chemiluminescence reactions and can be used for detecting hydrogen peroxide and evaluating urease activity . | ||||||||||||||||||||
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D-(-)-Lactic acid-13C | 99.9% | D-(-)-Lactic acid-13C ((R)-2-Hydroxypropionic acid-13C) is a 13C-labeled D-Lactic acid. D-(-)-Lactic acid-13C can be used as an internal standard and can also be used in studies such as metabolic tracing. | ||||||||||||||||||||
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D-(-)-Lactic acid-13C-1 | D-(-)-Lactic acid-13C-1 is the 13C labeled D-(-)-Lactic acid. D-(-)-Lactic acid is a normal intermediate in the fermentation (oxidation, metabolism) of sugar. D-(-)-Lactic acid is identified to be a competitive inhibitor of ProDH (proline dehydrogenase) in plants. | |||||||||||||||||||||
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L-Glyceric acid | L-Glyceric acid is a mainly urinary metabolite accumulating in rare inherited metabolic disease L-glyceric aciduria. L-Glyceric acid can be used to diagnose primary hyperoxaluria type 2 (PH2). L-Glyceric acid excretion to distinguish PH1 from PH2. | |||||||||||||||||||||
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D-Glyceric acid | D-Glyceric acid is an endogenous metabolite present in urine that can be used for the research of primary hyperoxaluria type I and glutaric acidemia type 2. | |||||||||||||||||||||
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2,3-Dihydroxybutanoic acid | 2,3-Dihydroxybutanoic acid is an anticancer agent that can be extracted from the leaves of Corydalis. 2,3-Dihydroxybutanoic acid has anticancer activity both in vitro and in vivo and is lethal to Ehrlich ascites tumor cells. | |||||||||||||||||||||
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Lactic acid | 85.50% | Lactic acid (DL-Lactic acid) is a hydroxycarboxylic acid receptor 1 (HCAR1) activator and an epigenetic modulator inducing lysine residues lactylation. Lactic acid is a glycolysis end-product, bridging the gap between glycolysis and oxidative phosphorylation. Lactic acid is an oncometabolite and has immune protective role of lactate in anti-tumor immunity. Lactic acid also has antimicrobial activity, which can be used as a food preservative. | ||||||||||||||||||||
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DL-Glyceric Acid (20% in water) | 95.0% | DL-Glyceric Acid (20% in water) is a metabolite of plants and mammals and exists in two configurations, D and L. | ||||||||||||||||||||
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L-Lactic acid | 99.57% | L-Lactic acid is a buildiing block which can be used as a precursor for the production of the bioplastic polymer poly-lactic acid. L-Lactic acid has antiproliferative activity. | ||||||||||||||||||||
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L-Lactic acid-13C3 | 99.9% | L-Lactic acid-13C3 is a 13C-labeled L-Lactic acid (HY-Y0479). L-Lactic acid-13C3 can be used for lactate metabolism research. | ||||||||||||||||||||
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L-Lactic acid-2-13C1 | L-Lactic acid-2-13C1 is the 13C-labeled L-Lactic acid (HY-Y0479). L-Lactic acid is a buildiing block which can be used as a precursor for the production of the bioplastic polymer poly-lactic acid. | |||||||||||||||||||||
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References
- [1]. Okada A, et al. Successful formation of calcium oxalate crystal deposition in mouse kidney by intraabdominal glyoxylate injection[J]. Urological research, 2007, 35(2): 89-99.
- [2]. Smirnov A Y, et al. Aminocoumaranones as chemiluminescence indicators of the urease activity and hydrogen peroxide[J]. Russian Journal of Bioorganic Chemistry, 2024, 50(1): 260-266.
- [3]. Norikura T, et al. Glyoxylic Acid, an α-Keto Acid Metabolite Derived from Glycine, Promotes Myogenesis in C2C12 Cells. Nutrients. 2023 Apr 4;15(7):1763. [Content Brief]
- [4]. Schmitt A, et al. Induction of reactive oxygen species and cell survival in the presence of advanced glycation end products and similar structures[J]. Biochimica et Biophysica Acta (BBA)-Molecular Cell Research, 2006, 1763(9): 927-936.
