563-96-2
563-96-2
Chemical Structure
2,2-Dihydroxyacetic acid
- CAS No.: 563-96-2
- Formula:C2H4O4
- Molecular Weight:92.05
IUPAC Name: 2,2-dihydroxyacetic acid
InChIKey: GOCCREQJUBABAL-UHFFFAOYSA-N
SMILES: O=C(C(O)O)O
Biological Activity: 2,2-Dihydroxyacetic acid is an endogenous metabolite, which is the monohydrate of Glyoxylic Acid. 2,2-Dihydroxyacetic acid may participate in the microbial glyoxylate cycle, induce an increase in reactive oxygen species, promote cell differentiation, and modify proteins to form advanced glycation end products (AGEs) (HY-NP165). 2,2-Dihydroxyacetic acid is associated with metabolic diseases such as primary hyperoxaluria[1][2][3][4].
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2,2-Dihydroxyacetic acid | 98.0% | 2,2-Dihydroxyacetic acid is an endogenous metabolite, which is the monohydrate of Glyoxylic Acid. 2,2-Dihydroxyacetic acid may participate in the microbial glyoxylate cycle, induce an increase in reactive oxygen species, promote cell differentiation, and modify proteins to form advanced glycation end products (AGEs) (HY-NP165). 2,2-Dihydroxyacetic acid is associated with metabolic diseases such as primary hyperoxaluria. | ||||||||||||||||||||
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2,2-Dihydroxyacetic acid (Standard) | ≥98% | 2,2-Dihydroxyacetic acid (Standard) is the analytical standard of 2,2-Dihydroxyacetic acid (HY-W019724). This product is intended for research and analytical applications. 2,2-Dihydroxyacetic acid is a key intermediate used in the synthesis of 3-aminocoumarone derivatives, which exhibit significant activity in chemiluminescence reactions and can be used for detecting hydrogen peroxide and evaluating urease activity . | ||||||||||||||||||||
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References
- [1]. Okada A, et al. Successful formation of calcium oxalate crystal deposition in mouse kidney by intraabdominal glyoxylate injection[J]. Urological research, 2007, 35(2): 89-99.
- [2]. Smirnov A Y, et al. Aminocoumaranones as chemiluminescence indicators of the urease activity and hydrogen peroxide[J]. Russian Journal of Bioorganic Chemistry, 2024, 50(1): 260-266.
- [3]. Norikura T, et al. Glyoxylic Acid, an α-Keto Acid Metabolite Derived from Glycine, Promotes Myogenesis in C2C12 Cells. Nutrients. 2023 Apr 4;15(7):1763. [Content Brief]
- [4]. Schmitt A, et al. Induction of reactive oxygen species and cell survival in the presence of advanced glycation end products and similar structures[J]. Biochimica et Biophysica Acta (BBA)-Molecular Cell Research, 2006, 1763(9): 927-936.
