6283-24-5
Chemical Structure
p-Aminophenylmercuric acetate
- CAS No.: 6283-24-5
- Formula:C8H9HgNO2
- Molecular Weight:351.75
IUPAC Name: acetoxy(4-aminophenyl)mercury
InChIKey: RXSUFCOOZSGWSW-UHFFFAOYSA-M
SMILES: O=C(C)O[Hg]C1=CC=C(C=C1)N
Biological Activity: p-Aminophenylmercuric acetate is an organomercurial activator of matrix metalloproteinases (MMP). P-Aminophenylmercuric acetate participates in the activation and inhibition of MMP-8 by attacking protein sulfhydryl or inducing cysteine switching reaction. p-Aminophenylmercuric acetate promotes the shedding of betacellulin precursor (pro-BTC). p-Aminophenylmercuric acetate influences the binding of agonists and antagonists to the opiate receptor[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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p-Aminophenylmercuric acetate | 98.32% | p-Aminophenylmercuric acetate is an organomercurial activator of matrix metalloproteinases (MMP). P-Aminophenylmercuric acetate participates in the activation and inhibition of MMP-8 by attacking protein sulfhydryl or inducing cysteine switching reaction. p-Aminophenylmercuric acetate promotes the shedding of betacellulin precursor (pro-BTC). p-Aminophenylmercuric acetate influences the binding of agonists and antagonists to the opiate receptor. | ||||||||||||||||||||
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Similarity Score 0.81
HY-W0088184'-Aminoacetophenone -
Similarity Score 0.79
HY-W019294p-(Methoxycarbonylmethyl)aniline -
Similarity Score 0.76
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Similarity Score 0.76
HY-754764-Aminophenylacetic acid -
Similarity Score 0.74
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Similarity Score 0.73
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Similarity Score 0.72
HY-W0080153-Aminophenylacetic acid -
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References
- [1]. Sanderson M P, et al. ADAM10 mediates ectodomain shedding of the betacellulin precursor activated by p-aminophenylmercuric acetate and extracellular calcium influx[J]. Journal of Biological Chemistry, 2005, 280(3): 1826-1837. [Content Brief]
- [2]. PASTERNAK G W, et al. Differential effects of protein-modifying reagents on receptor binding of opiate agonists and antagonists[J]. Molecular Pharmacology, 1975, 11(3): 340-351. [Content Brief]
- [3]. Gendron R, et al. Inhibition of the activities of matrix metalloproteinases 2, 8, and 9 by chlorhexidine[J]. Clinical Diagnostic Laboratory Immunology, 1999, 6(3): 437-439. [Content Brief]
