6402-36-4
6402-36-4
Chemical Structure
Traumatic Acid
- CAS No.: 6402-36-4
- Formula:C12H20O4
- Molecular Weight:228.28
IUPAC Name: (E)-dodec-2-enedioic acid
InChIKey: MAZWDMBCPDUFDJ-VQHVLOKHSA-N
SMILES: O=C(O)/C=C/CCCCCCCCC(O)=O
Biological Activity: Traumatic Acid is a wound healing agent and a cytokinin (phytohormone). Traumatic Acid enhances the biosynthesis of collagen in cultured human skin fibroblasts. Traumatic Acid inhibits MCF-7 breast cancer cells viability and enhances apoptosis and oxidative stress. Traumatic Acid can be used in studies of cancer, circulatory disorders (including arterial hypertension), and skin diseases associated with oxidative stress and impaired collagen biosynthesis[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Traumatic Acid | 99.34% | Traumatic Acid is a wound healing agent and a cytokinin (phytohormone). Traumatic Acid enhances the biosynthesis of collagen in cultured human skin fibroblasts. Traumatic Acid inhibits MCF-7 breast cancer cells viability and enhances apoptosis and oxidative stress. Traumatic Acid can be used in studies of cancer, circulatory disorders (including arterial hypertension), and skin diseases associated with oxidative stress and impaired collagen biosynthesis. | ||||||||||||||||||||
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Traumatic Acid (Standard) | 99.67% | Traumatic Acid (Standard) is the analytical standard of Traumatic Acid. This product is intended for research and analytical applications. Traumatic Acid is a wound healing agent and a cytokinin (phytohormone). Traumatic Acid enhances the biosynthesis of collagen in cultured human skin fibroblasts. Traumatic Acid inhibits MCF-7 breast cancer cells viability and enhances apoptosis and oxidative stress. Traumatic Acid can be used in studies of cancer, circulatory disorders (including arterial hypertension), and skin diseases associated with oxidative stress and impaired collagen biosynthesis. | ||||||||||||||||||||
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Myristoleic acid (Standard) | ≥98% | Myristoleic acid (Standard) is the analytical standard of Myristoleic acid. This product is intended for research and analytical applications. Myristoleic acid, a cytotoxic component in the extract from Serenoa repens, induces apoptosis and necrosis in human prostatic LNCaP cells. | ||||||||||||||||||||
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10(E)-Pentadecenoic acid | 99.90% | 10 (E)-Pentadecenoic acid (trans-10-Pentadecenoic acid) is a melanin synthesis inhibitor. 10 (E)-Pentadecenoic acid inhibits nuclear translocation and reduces the protein level of phosphorylated microphthalmia-associated transcription factor (MITF), as well as decreases intracellular tyrosinase activity. 10 (E)-Pentadecenoic acid can be used in the research of skin pigmentation disorders. | ||||||||||||||||||||
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10(Z)-Pentadecenoic acid | 99.86% | 10(Z)-Pentadecenoic acid (cis-10-Pentadecenoic acid) is a monounsaturated fatty acid with Z configuration. 10(Z)-Pentadecenoic acid is degraded via two pathways, reductase-isomerase and epimerase. 10(Z)-Pentadecenoic acid is one of the major monounsaturated FAME components evaluated as biodiesel feedstock in Chlorella sp. RCS2. 10(Z)-Pentadecenoic acid weakly inhibits IFN-γ-induced IDO-1 activity and kynurenine production. 10(Z)-Pentadecenoic acid is a non-esterified fatty acid downregulated in adolescent depression and has diagnostic discriminatory potential. 10(Z)-Pentadecenoic acid is used in studies related to depression, inflammation, and lipid metabolism. | ||||||||||||||||||||
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Myristelaidic acid | 99.9% | Myristelaidic acid (trans-9-Tetradecenoic acid), a 14-carbon trans fatty acid, is the trans isomer of Myristoleic acid. Myristelaidic acid is found in most animal fats. | ||||||||||||||||||||
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10-Oxo-11(E)-octadecenoic acid | 10-Oxo-11(E)-octadecenoic acid is an ester product. | |||||||||||||||||||||
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2(Z)-Tetradecenoic acid | 2(Z)-Tetradecenoic acid is a fatty acid. | |||||||||||||||||||||
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7-Hexadecenedioic acid | 7-Hexadecenedioic acid is an asymmetric olefinic aliphatic α,ω-dicarboxylic acid. When 7-Hexadecenedioic acid undergoes esterification with n-butanol under catalysis by PPL, it produces a 1:1 mixture of its two monobutyl ester isomers. | |||||||||||||||||||||
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Decanedioic acid ammonium | Decanedioic acid (ammonium) (Sebacic acid (ammonium); Ammonium decanedioate; Diammonium sebacate) is a PROTAC linker that can be used in the synthesis of PROTACs. | |||||||||||||||||||||
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Dodecanedioic acid | 98.0% | Dodecanedioic acid is an orally active straight-chain dicarboxylic acid. As an alternative energy substrate between lipids and carbohydrates, Dodecanedioic acid can be rapidly oxidized during exercise, reducing muscle fatigue without stimulating insulin secretion. Dodecanedioic acid also exhibits blood glucose-lowering activity in non-insulin-dependent diabetes mellitus. | ||||||||||||||||||||
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Dodecanedioic Acid-13C12 | Dodecanedioic Acid-13C12 is the 13C-labeled Dodecanedioic acid (HY-W012241). Dodecanedioic acid is an orally active straight-chain dicarboxylic acid. As an alternative energy substrate between lipids and carbohydrates, Dodecanedioic acid can be rapidly oxidized during exercise, reducing muscle fatigue without stimulating insulin secretion. Dodecanedioic acid also exhibits blood glucose-lowering activity in non-insulin-dependent diabetes mellitus. | |||||||||||||||||||||
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References
- [1]. Jabłońska-Trypuć A, et al. Traumatic Acid Reduces Oxidative Stress and Enhances Collagen Biosynthesis in Cultured Human Skin Fibroblasts.Lipids. 2016 Sep;51(9):1021-35. [Content Brief]
- [2]. Jabłońska-Trypuć A, et al. Traumatic acid toxicity mechanisms in human breast cancer MCF-7 cells. Regul Toxicol Pharmacol. 2019 Aug;106:137-146. [Content Brief]
