65-61-2
65-61-2
Chemical Structure
Acridine Orange hydrochloride
- CAS No.: 65-61-2
- Formula:C17H20ClN3
- Molecular Weight:301.82
IUPAC Name: N3,N3,N6,N6-tetramethylacridine-3,6-diamine hydrochloride
InChIKey: VSTHNGLPHBTRMB-UHFFFAOYSA-N
SMILES: CN(C)C1=CC=C2C(N=C3C=C(N(C)C)C=CC3=C2)=C1.[H]Cl
Biological Activity: Acridine Orange hydrochloride is a cell-penetrable nucleic acid-selective fluorescent dye. Acridine Orange hydrochloride produces orange fluorescence when it binds to ssDNA or RNA, and green fluorescence when it binds to dsDNA (Ex: 488 nM; Em: green fluorescence at 530 nm, orange fluorescence at 640 nm)[1][2][3].
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Acridine Orange hydrochloride | 99.65% | Acridine Orange hydrochloride is a cell-penetrable nucleic acid-selective fluorescent dye. Acridine Orange hydrochloride produces orange fluorescence when it binds to ssDNA or RNA, and green fluorescence when it binds to dsDNA (Ex: 488 nM; Em: green fluorescence at 530 nm, orange fluorescence at 640 nm). | ||||||||||||||||||||
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Acridine Orange hydrochloride (Standard) | ≥98% | Acridine Orange hydrochloride (Standard) is the analytical standard of Acridine Orange hydrochloride (HY-101879). This product is intended for research and analytical applications. Acridine Orange hydrochloride is a cell-penetrable nucleic acid-selective fluorescent dye. Acridine Orange hydrochloride produces orange fluorescence when it binds to ssDNA or RNA, and green fluorescence when it binds to dsDNA (Ex: 488 nM; Em: green fluorescence at 530 nm, orange fluorescence at 640 nm). | ||||||||||||||||||||
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Acridine Orange hydrochloride (solution) | Acridine Orange hydrochloride (solution) is a cell-penetrable nucleic acid-selective fluorescent dye. Acridine Orange hydrochloride produces orange fluorescence when it binds to ssDNA or RNA, and green fluorescence when it binds to dsDNA (Ex: 488 nM; Em: green fluorescence at 530 nm, orange fluorescence at 640 nm) . Solvent and Concentration: Sterile water: 10 mg/mL The 1 mL volume is defined as the base specification. All larger sizes correspond to incremental volumes of this base. |
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References
- [1]. McMaster GK, et al. Analysis of single- and double-stranded nucleic acids on polyacrylamide and agarosegels by using glyoxal and acridine orange. Proc Natl Acad Sci U S A. 1977 Nov;74(11):4835-8. [Content Brief]
- [2]. Traganos F, et al. Simultaneous staining of ribonucleic and deoxyribonucleic acids in unfixed cells using acridine orange in a flow cytofluorometric system. J Histochem Cytochem. 1977 Jan;25(1):46-56. [Content Brief]
- [3]. Byvaltsev VA, et al. Acridine Orange: A Review of Novel Applications for Surgical Cancer Imaging and Therapy. Front Oncol. 2019 Sep 24;9:925. [Content Brief]
