BRD-4592
BRD-4592 is an allosteric inhibitor targeting Mycobacterium tuberculosis tryptophan synthase (TrpAB). BRD-4592 binds at the α-β-subunit interface of TrpAB, with an IC50 of 70.9 nM for the α-subunit and 22.6 nM for the β-subunit.
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- CAS. Nr.: 2119598-24-0
- Formel: C17H15FN2O
- Molecular Weight:282.31
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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Help & FAQs
Biologische Aktivität
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HepG2 | CC50 |
>100 μM
Compound: BRD-4592
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Cytotoxicity against human HepG2 cells
Cytotoxicity against human HepG2 cells
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[PMID: 31627992] |
Chemical Information
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CAS. Nr. 2119598-24-0
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Molecular Weight 282.31
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Formel C17H15FN2O
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SMILES
N#C[C@H]1[C@H](C2=CC=C(C3=C(C=CC=C3)F)C=C2)[C@@H](N1)CO
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
BRD-4592 Related Classifications
HY-122016A Related Classifications
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