Curculigoside C
Curculigoside C is a phenolic glucoside with potent antioxidative and neuroprotective activities. Curculigoside C shows IC50 values of 0.25 mM and 0.88 mM for hydroxyl radicals and superoxide anion radicals, respectively.
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- CAS. Nr.: 851713-74-1
- Formel: C22H26O12
- Molecular Weight:482.43
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
Curculigoside C displays neuroprotective effect in the evaluation of salvaging SY5Y cell death induced by H2O2[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Pharmacokinetic parameters of CC in rat plasma after intragastric administration[1].
| Dose (mg/kg) | t1/2 (h) | AUC0-60 (μg/L/h) | AUC0-∞ (μg/L/h) | F (%) | Vd (L/kg) | CLz (L/h/kg) | |
| 15 | 2.022 ± 0.184 | 0.106 ± 0.149 | 62.731 ± 10.149 | 66.310 ± 10.563 | 2.01 | 673.157 ± 116.509 | 231.036 ± 36.69 |
| 30 | 2.061 ± 0.325 | 0.111 ± 0.043 | 133.17 ± 48.434 | 140.656 ± 48.335 | 2.13 | 722.605 ± 316.306 | 234.188 ± 74.864 |
| 60 | 2.048 ± 0.227 | 0.111 ± 0.043 | 299.155 ± 80.954 | 316.980 ± 91.704 | 2.39 | 585.344 ± 124.289 | 201.905 ± 55.193 |
| 2.0 (i.v) | 1.153 ± 0.203 | - | 416.700 ± 70.401 | 420.700 ± 70.690 | - | 8.122 ± 1.973 | 4.869 ± 0.834 |
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 851713-74-1
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Molecular Weight 482.43
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Formel C22H26O12
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SMILES
OC[C@H]([C@H]([C@@H]([C@H]1O)O)O)O[C@H]1OC(C=CC(O)=C2)=C2COC(C3=C(C(O)=CC=C3OC)OC)=O
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Structure Classification
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Initial Source
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Wu Q, et al. Antioxidative phenols and phenolic glycosides from Curculigo orchioides. Chem Pharm Bull (Tokyo). 2005 Aug;53(8):1065-7. [Content Brief]
[2]. Di Wu, et al. Pharmacokinetic and Metabolism Studies of Curculigoside C by UPLC-MS/MS and UPLC-QTOF-MS. Molecules. 2018 Dec 21;24(1):21. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Curculigoside C Related Classifications
HY-N9095 Related Classifications
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