Cd200 - CD200 molecule Gene

Also Known as OX2; Mox2

Species: Mus musculus

Gene Type: protein coding
Gene ID: 17470

Summary

Predicted to enable protein binding activity involved in heterotypic cell-cell adhesion. Involved in negative regulation of cell population proliferation; negative regulation of macrophage activation; and negative regulation of neuroinflammatory response. Located in cell surface. Is expressed in several structures, including anterior naris; aorta; bone; nervous system; and retina. Used to study autoimmune disease. Orthologous to human CD200 (CD200 molecule). [provided by Alliance of Genome Resources, Apr 2022]

Cd200 Products (2)

mRNA Protein Name
NM_001358443.1 NP_001345372.1 OX-2 membrane glycoprotein isoform 2
NM_010818.3 NP_034948.3 OX-2 membrane glycoprotein isoform 1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Verweise Source
enables protein binding IPI
IPI: Inferred from physical interaction
15274657 MGI
Biological Process GO Annotation Evidence Verweise Source
involved in negative regulation of cell population proliferation IMP
IMP: Inferred from mutant phenotype
11099416 MGI
involved in negative regulation of macrophage activation IMP
IMP: Inferred from mutant phenotype
11099416 MGI
involved in negative regulation of neuroinflammatory response IMP
IMP: Inferred from mutant phenotype
11099416 MGI
Cellular Component GO Annotation Evidence Verweise Source
located in cell surface IDA
IDA: Inferred from direct assay
11099416 MGI
is active in postsynaptic density IDA
IDA: Inferred from direct assay
27565350 MGI
is active in presynaptic active zone IDA
IDA: Inferred from direct assay
27565350 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

OX-2 membrane glycoprotein

  • CD200 antigen

  • MRC OX-2 antigen

  • antigen identified by monoclonal antibody MRC OX-2

Recombinant Cd200 Proteins

Art. -Nr. Produktname Accession Reinheit
HY-P72889 CD200 Protein, Mouse (HEK293, His) O54901 (Q31-G232) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (9)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS18434 Cd200r1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS02205 CD200 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS02206 CD200R1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS02207 CD200R1L Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16811 Cd200 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21271 Cd200r1l Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23251 Cd200 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24915 Cd200r1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27789 Cd200r1l Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (4)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-P992113 Evabosmig Activator / Unkown
HY-P990479 Anti-OX2R/CD200R1 Antibody Inhibitor / Unkown
HY-P991452 Anti-CD200R1/OX2R Antibody (I-4P) Inhibitor / Unkown
HY-P992162 23ME-00610 / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cd200 NCBI NCBI:4345