Linezolid-d3
Based on 1 publication(s) in Google Scholar
Linezolid-d3 (PNU-100766-d3) is a deuterium labeled Linezolid (PNU-100766). Linezolid is a synthetic antibiotic that acts by inhibiting the initiation of bacterial protein synthesis.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit: 99.80%
- CAS. Nr.: 1127120-38-0
- Formel: C16H17D3FN3O4
- Molecular Weight:340.36
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Speicherung:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Publications Citing Use of MedChemExpress (MCE) Linezolid-d3
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Biologische Aktivität
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS. Nr. 1127120-38-0
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Unlabeled Cas 165800-03-3
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Appearance Solid
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Molecular Weight 340.36
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Formel C16H17D3FN3O4
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Color White to off-white
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SMILES
O=C(O[C@H]1CNC(C([2H])([2H])[2H])=O)N(C1)C2=CC(F)=C(N3CCOCC3)C=C2
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Synonyms
PNU-100766-d3
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
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Rapid Commun Mass Spectrom
2025;39(20):e10103. PMID: 40589310
Lösungsmittel & Löslichkeit
DMSO : ≥ 20 mg/mL (58.76 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
DMF : ≥ 10 mg/mL (29.38 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (272 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMF / DMSO | 1 mM | 2.9381 mL | 14.6903 mL | 29.3807 mL | 73.4516 mL |
| 5 mM | 0.5876 mL | 2.9381 mL | 5.8761 mL | 14.6903 mL | |
| 10 mM | 0.2938 mL | 1.4690 mL | 2.9381 mL | 7.3452 mL | |
| 15 mM | 0.1959 mL | 0.9794 mL | 1.9587 mL | 4.8968 mL | |
| 20 mM | 0.1469 mL | 0.7345 mL | 1.4690 mL | 3.6726 mL | |
| 25 mM | 0.1175 mL | 0.5876 mL | 1.1752 mL | 2.9381 mL | |
| DMSO | 30 mM | 0.0979 mL | 0.4897 mL | 0.9794 mL | 2.4484 mL |
| 40 mM | 0.0735 mL | 0.3673 mL | 0.7345 mL | 1.8363 mL | |
| 50 mM | 0.0588 mL | 0.2938 mL | 0.5876 mL | 1.4690 mL |