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Art. -Nr.: HY-173305

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Mpro/PLPro-IN-2

Mpro/PLPro-IN-2 (Compound 22l) is a non-covalent competitive dual inhibitor of the papain-like protease and main protease of SARS-CoV-2, with a K_i of 0.2 μM for the papain-like protease and a K_i of 1.1 μM for the main protease. Mpro/PLPro-IN-2 can be used in the research field of anti-SARS-CoV-2.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

Formel: C₁₆H₁₇N₃O₃S
Molecular Weight:331.39

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

Mpro/PLPro-IN-2 Chemical Structure

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Preis

Verfügbarkeit

Menge

Amount: USD 0.00

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität

Beschreibung

Mpro/PLPro-IN-2 (Compound 22l) is a non-covalent competitive dual inhibitor of the papain-like protease and main protease of SARS-CoV-2, with a K_i of 0.2 μM for the papain-like protease and a K_i of 1.1 μM for the main protease^[1]. Mpro/PLPro-IN-2 can be used in the research field of anti-SARS-CoV-2^[1].

Chemical Information

Molecular Weight 331.39
Formel C₁₆H₁₇N₃O₃S
SMILES

O=C(NNC1=NC(C)=C(C(OCC)=O)S1)/C=C/C2=CC=CC=C2
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Alli VJ, et al. Development of acylhydrazone linked thiazoles as non-covalent dual inhibitors of SARS-CoV-2 proteases. Eur J Med Chem. 2025 Jun 5;290:117509. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Keywords

MOQ

Minimum order quantity

100 mg

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