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Cat. No.: HY-100784R

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Dihydrokainic acid (Standard)

Dihydrokainic acid (Standard) is the analytical standard of Dihydrokainic acid. This product is intended for research and analytical applications. Dihydrokainic acid (DHK) is a glutamate transporter GLT1 (EAAT2) inhibitor. Dihydrokainic acid impairs novel object recognition (NOR) memory performance in mice. Dihydrokainic acid also shows epileptogenic effects.

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CAS No.: 52497-36-6
Formule: C₁₀H₁₇NO₄
Masse moléculaire:215.25

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Please store the product under the recommended conditions in the Certificate of Analysis.

Dihydrokainic acid (Standard) Chemical Structure

CAS No.: 52497-36-6

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 52497-36-6
Masse moléculaire 215.25
Formule C₁₀H₁₇NO₄
SMILES

O=C(O)C[C@@H]1[C@@H](C(O)=O)NC[C@@H]1C(C)C
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Références

[1]. Lehmann A, et al. Dihydrokainic acid affects extracellular taurine and phosphoethanolamine levels in the hippocampus. Neuroscience Letters, 1983, 38(1): 67-72.

[2]. Bouazzaoui M, et al. Kainic acid, AMPA, and dihydrokainic acid effect on uptake and efflux of D-[3H] aspartic acid in cerebellar slices. Neurochem Res. 1996 Dec;21(12):1527-33. [Content Brief]

[3]. Butcher SP, et al. On the epileptogenic effects of kainic acid and dihydrokainic acid in the dentate gyrus of the rat. Neuropharmacology. 1988 Apr;27(4):375-81. [Content Brief]

[4]. Tian SW, et al. Glutamate transporter GLT1 inhibitor dihydrokainic acid impairs novel object recognition memory performance in mice. Physiol Behav. 2019 Feb 1;199:28-32. [Content Brief]

[5]. Muñoz M D, et al. Effects of dihydrokainic acid of extracellular amino acids and neuronal excitability in the in vivo rat hippocampus. Neuropharmacology, 1987, 26(1): 1-8.

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Dihydrokainic acid (Standard)

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Dihydrokainic acid (Standard)