Txn1 - thioredoxin 1 Gene

Also Known as ADF; Txn; Trx1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 22166

Summary

Enables protein-disulfide reductase activity. Acts upstream of or within cell redox homeostasis; negative regulation of protein export from nucleus; and negative regulation of transcription by RNA polymerase II. Located in cytosol and nucleus. Is expressed in central nervous system; skeleton; and submandibular gland primordium. Orthologous to human TXN (thioredoxin). [provided by Alliance of Genome Resources, Apr 2022]

Txn1 Products (1)

mRNA Protein Name
NM_011660.3 NP_035790.1 thioredoxin

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
18555775 MGI
enables protein-disulfide reductase activity IDA
IDA: Inferred from direct assay
18555775 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within cell redox homeostasis IDA
IDA: Inferred from direct assay
18555775 MGI
acts upstream of or within negative regulation of protein export from nucleus IDA
IDA: Inferred from direct assay
18555775 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IGI
IGI: Inferred from genetic interaction
18555775 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
11213470 MGI
located in cytosol IDA
IDA: Inferred from direct assay
18555775 MGI
located in nucleus IDA
IDA: Inferred from direct assay
11213470 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

thioredoxin

  • ATL-derived factor

  • trx

Recombinant Txn1 Proteins

Cat. No. Product Name Accession Purity
HY-P73432 Thioredoxin/TRX Protein, Mouse P10639 (M1-A105) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P73432A Thioredoxin/TRX Protein, Mouse (N-His) P10639 (M1-A105) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15287 TXN Human Pre-designed siRNA Set A Pre-designed Set / Unkown