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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
13 Results for "
SIAH
" in MedChemExpress (MCE) Product Catalog:
Products (13)
13 Results for "SIAH" in MCE Product Catalog:
3
3 Cited Publications
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BI-3802, a chemical probe, is a highly potent BCL6 degrader and inhibits the Bric-à-brac (BTB) domain of BCL6 with an IC50 of ≤3 nM. BI-3802 induces the polymerization of BCL6 and promotes BCL6 degration depended on E3 ligase SIAH1. BI-3802 has antitumor activity .
Cat. No.: HY-RS12891
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SIAH1 Human Pre-designed siRNA Set A contains three designed siRNAs for SIAH1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS12892
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SIAH2 Human Pre-designed siRNA Set A contains three designed siRNAs for SIAH2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS12893
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SIAH3 Human Pre-designed siRNA Set A contains three designed siRNAs for SIAH3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS29319
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Siah1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Siah1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS21046
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Siah2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Siah2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS27564
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Siah2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Siah2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P87272
Synonyms: E3 ubiquitin-protein ligase SIAH1 antibody; FLJ08065 antibody; hSIAH1 antibody; HUMSIAH antibody; Seven in absentia homolog 1 (Drosophila) antibody; Seven in absentia homolog 1 antibody; SIAH 1 antibody; SIAH 1a antibody; SIAH E3 ubiquitin protein ligase 1 antibody; SIAH-1 antibody
Cat. No.: HY-182399
CAS No.: 2421117-94-2
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BC-DXI-495 is a AIMP2-DX2 inhibitor. BC-DXI-495 disrupts the interaction of HSP70 and destabilizes DX2. BC-DXI-495 induces DX2 degradation via Siah1-mediated ubiquitination. BC-DXI-495 exerts tumor suppressive activity in cancer cells. BC-DXI-495 serves as a chemical probe to elucidate the mechanism of action of arylsulfonamide-based DX2 inhibitors. BC-DXI-495 can be used in lung cancer research .
Cat. No.: HY-108705R
CAS No.: 2166387-65-9
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BI-3802 (Standard) is the analytical standard of BI-3802 (HY-108705). This product is intended for research and analytical applications. BI-3802, a chemical probe, is a highly potent BCL6 degrader and inhibits the Bric-à-brac (BTB) domain of BCL6 with an IC50 of ≤3 nM. BI-3802 induces the polymerization of BCL6 and promotes BCL6 degration depended on E3 ligase SIAH1. BI-3802 has antitumor activity .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
