CACYBP Antibody
(Synonyms: S100A6BP, SIP, PNAS-107, CACYBP, Calcyclin-binding protein, CacyBP, hCacyBP, S100A6-binding protein, Siah-interacting protein)CACYBP Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to CACYBP.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, ICC/IF
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
|
ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
|---|---|---|
| Dilution Ratio | 1:1000-2000 | 1:50-200 |
Product Details
CACYBP Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to CACYBP.
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Host Rabbit
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Clonality Polyclonal
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Species ReactivityHuman, Mouse, Rat
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Observed Molecular WeightObserved band size: 26 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 8; 21; 26 kDa
Purified recombinant protein of human CACYBP
Endogenous
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
CACYBP may be involved in calcium-dependent ubiquitination and subsequent proteasomal degradation of target proteins. Probably serves as a molecular bridge in ubiquitin E3 complexes. Participates in the ubiquitin-mediated degradation of beta-catenin (CTNNB1)
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Subcellular Localization
Nucleus; Cytoplasm
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Isoforms & Post-Translational Modification
CACYBP has 3 isoforms, Q9HB71-1: amino acid length is 228, molecular weight is 26210 Da (predicted); Q9HB71-2: amino acid length is 80, molecular weight is 8956 Da (predicted); Q9HB71-3: amino acid length is 185, molecular weight is 21228 Da (predicted).在丝氨酸残基上发生磷酸化。视黄酸(RA)诱导时或高钙浓度下会发生磷酸化CACYBP 存在 3 个异构体，Q9HB71-1：氨基酸个数为 228 个，分子量为 26210 Da (预测)；Q9HB71-2：氨基酸个数为 80 个，分子量为 8956 Da (预测)；Q9HB71-3：氨基酸个数为 185 个，分子量为 21228 Da (预测)。Phosphorylated on serine residues. Phosphorylated upon induction by RA or at high calcium concentrations
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Subunit
Homodimer.
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SwissProt ID
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Synonyms
S100A6BP, SIP, PNAS-107, CACYBP, Calcyclin-binding protein, CacyBP, hCacyBP, S100A6-binding protein, Siah-interacting protein
Documentation
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