Formate dehydrogenase
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Formate dehydrogenase is a class of oxidoreductases widely distributed in bacteria, fungi, plants and animals. Formate dehydrogenase catalyzes the reversible conversion between formic acid and carbon dioxide, accompanied by redox reactions of the coenzyme NAD+/NADH or other electron carriers.
For research use only. We do not sell to patients.
- CAS No.: 9028-85-7
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Overexpression of formate dehydrogenase (1 g/L formate; 48-96 h) in S. cerevisiae FA enhances the tolerance of S. cerevisiae FA to 1 g/L formate, decomposes formate into CO2, and simultaneously improves glucose utilization, cell density and cell viability[1].
Overexpression of formate dehydrogenase under conditions of 4 g/L acetic acid and 48-96 h in S. cerevisiae FA enhances the acetic acid tolerance of S. cerevisiae FA. By converting CO2 into formate and additionally producing ATP, it enables faster glucose utilization, higher ethanol yield, higher cell density, and stronger cell viability[1].
Formate dehydrogenase enhances aluminum tolerance in tobacco[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1.2.1.2
≥5 U/mg protein
One unit is defined as the amount of enzyme that will oxidation of 1 μmol of formate per min to CO2 at pH 7.6 and 37°C
Chemical Information
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CAS No. 9028-85-7
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Appearance Solid
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Color White to light yellow
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SMILES
[Formate dehydrogenase]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Data Sheet (264 KB)
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SDS (418 KB)
- English - EN (418 KB)
- Français - FR (418 KB)
- Deutsch - DE (418 KB)
- Norwegian - NO (418 KB)
- Español - ES (418 KB)
- Swedish - SV (418 KB)
- Italian - IT (418 KB)
- Korean - KR (418 KB)
- Portuguese - PT (418 KB)
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Handling Instructions (2659 KB)
References
[1]. Du C, et al. Formate Dehydrogenase Improves the Resistance to Formic Acid and Acetic Acid Simultaneously in Saccharomyces cerevisiae. Int J Mol Sci. 2022 Mar 21;23(6):3406. [Content Brief]
[2]. Xie Y, et al. The formate dehydrogenase enhances aluminum tolerance of tobacco. J Genet. 2023;102:50. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Formate dehydrogenase Related Classifications
HY-P2907 Related Classifications
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