GSK2188764
GSK2188764 is a Toxoplasma gondii rhoptry protein 18 (ROP18) inhibitor with reported IC50 values of 7.49 μM against Toxoplasma gondii. GSK2188764 inhibits serine-threonine kinase activity of ROP18 in vitro.GSK2188764 can be used for the research of toxoplasmosis.
For research use only. We do not sell to patients.
- CAS No.: 1849587-68-3
- Formula: C17H16Cl2N6O
- Molecular Weight:391.26
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Chemical Information
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Biological Activity
GSK2188764 (up to 10 μM; 10 min pre-incubation, 3 h reaction) weakly inhibits recombinant Toxoplasma gondii ROP18 kinase activity in vitro, with an IC50 of 7.49 μM against the FL-E substrate and >10 μM against the FL-T and FL-8 substrates[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1849587-68-3
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Molecular Weight 391.26
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Formula C17H16Cl2N6O
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SMILES
O=C1NC=CC=2N=C(N=C(NC=3C=C(Cl)C=C(Cl)C3)C12)NC4CNCC4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
GSK2188764 Related Classifications
HY-120808 Related Classifications
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