BChE-IN-33
BChE-IN-33 (compound 4r), an arylaminonaphthol derivative, is a potent butyrylcholinesterase (BChE) inhibitor with an IC50 of 14.78 µM. BChE-IN-33 also inhibits CYP2C19, CYP2C9, CYP2D6. BChE-IN-33 shows potent antioxidant activity with IC50 values of 150.48 μM, 2.56 μM and 4.61 μM by DPPH, ABTS, Ferric-phenanthroline assay, respectively. BChE-IN-33 has the potential for Alzheimer research.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Fòrmula: C23H17ClN2O3
- Peso molecular:404.85
-
Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
|
BChE 14.78 nM (IC50) |
CYP2C19 |
CYP2C9 |
CYP2D6 |
Chemical Information
-
Peso molecular 404.85
-
Fòrmula C23H17ClN2O3
-
SMILES
OC1=CC=C2C=CC=CC2=C1C(NC3=CC=C(Cl)C=C3)C4=CC=CC([N+]([O-])=O)=C4
-
Envío
Room temperature in continental US; may vary elsewhere.
-
Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)