TGFB1 - transforming growth factor beta 1 Gene

Also Known as CED; LAP; DPD1; TGFB; IBDIMDE; TGFbeta; TGF-beta1

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 7040

About TGFB1

Cytogenetic location: 19q13.2 Genomic coordinates (GRCh38): 19:41,330,323-41,353,922 (from NCBI)

This gene has 5 transcripts (splice variants), 210 orthologues, 31 paralogues and is associated with 7 phenotypes. Broad expression in spleen (RPKM 38.0), bone marrow (RPKM 32.1) and 23 other tissues.

Summary

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of Smad Family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with Other TGFB family members. This encoded protein regulates cell proliferation, differentiation and growth, and can modulate expression and activation of Other growth factors including interferon gamma and tumor necrosis factor alpha. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease. [provided by RefSeq, Aug 2016]

TGFB1 Products (3)

mRNA	Protein	Name
NM_000660.7	NP_000651.3	transforming growth factor beta-1 proprotein preproprotein
XM_011527242.3	XP_011525544.1	transforming growth factor beta-1 proprotein isoform X1
NM_000660.7	NP_000651.3	transforming growth factor beta-1 proprotein preproprotein

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Referencias	Source
enables cytokine activity	IDA IDA: Inferred from direct assay	26572508	GOA
enables deubiquitinase activator activity	IDA IDA: Inferred from direct assay	32644293	GOA
enables enzyme binding	IPI IPI: Inferred from physical interaction	19366691	GOA
enables growth factor activity	IMP IMP: Inferred from mutant phenotype	31368162	GOA
enables identical protein binding	IPI IPI: Inferred from physical interaction	21677751	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	1326540	GOA
enables protein serine/threonine kinase activator activity	IDA IDA: Inferred from direct assay	32644293	GOA
enables type I transforming growth factor beta receptor binding	IMP IMP: Inferred from mutant phenotype	8167376	GOA
enables type I transforming growth factor beta receptor binding	IPI IPI: Inferred from physical interaction	10885742	GOA
enables type II transforming growth factor beta receptor binding	IDA IDA: Inferred from direct assay	11157754	GOA
enables type II transforming growth factor beta receptor binding	IMP IMP: Inferred from mutant phenotype	8167376	GOA
enables type II transforming growth factor beta receptor binding	IPI IPI: Inferred from physical interaction	1333888	GOA
enables type III transforming growth factor beta receptor binding	IMP IMP: Inferred from mutant phenotype	8167376	GOA
enables type III transforming growth factor beta receptor binding	IPI IPI: Inferred from physical interaction	10092230	GOA

Biological Process GO Annotation	Evidence	Referencias	Source
involved in ATP biosynthetic process	IDA IDA: Inferred from direct assay	10513816	GOA
involved in aortic valve morphogenesis	IMP IMP: Inferred from mutant phenotype	26634652	GOA
NOT involved in apoptotic process	IMP IMP: Inferred from mutant phenotype	3470709	GOA
involved in cell-cell junction organization	IDA IDA: Inferred from direct assay	18505915	GOA
involved in cellular response to hypoxia	IMP IMP: Inferred from mutant phenotype	31368162	GOA
involved in cellular response to low-density lipoprotein particle stimulus	IMP IMP: Inferred from mutant phenotype	32141990	GOA
involved in cellular response to transforming growth factor beta stimulus	IDA IDA: Inferred from direct assay	19736306	GOA
involved in cellular response to transforming growth factor beta stimulus	IGI IGI: Inferred from genetic interaction	22269326	GOA
involved in chondrocyte differentiation	IDA IDA: Inferred from direct assay	15040835	GOA
acts upstream of epithelial to mesenchymal transition	IDA IDA: Inferred from direct assay	28373289	GOA
acts upstream of or within epithelial to mesenchymal transition	IDA IDA: Inferred from direct assay	29529050	GOA
involved in epithelial to mesenchymal transition	IDA IDA: Inferred from direct assay	25893292	GOA
involved in extracellular matrix assembly	IDA IDA: Inferred from direct assay	19734317	GOA
involved in extrinsic apoptotic signaling pathway	IDA IDA: Inferred from direct assay	15334054	GOA
involved in hematopoietic progenitor cell differentiation	IDA IDA: Inferred from direct assay	15451575	GOA
involved in hyaluronan catabolic process	IDA IDA: Inferred from direct assay	17324121	GOA
involved in membrane protein intracellular domain proteolysis	IDA IDA: Inferred from direct assay	25310401	GOA
involved in negative regulation of DNA-templated transcription	IDA IDA: Inferred from direct assay	15702480	GOA
involved in negative regulation of biomineral tissue development	IDA IDA: Inferred from direct assay	26634652	GOA
involved in negative regulation of blood vessel endothelial cell migration	IDA IDA: Inferred from direct assay	18555217	GOA
involved in negative regulation of cell cycle	IDA IDA: Inferred from direct assay	11502704	GOA
involved in negative regulation of cell differentiation	IEP IEP: Inferred from expression pattern	19357233	GOA
involved in negative regulation of cell growth	IDA IDA: Inferred from direct assay	15334054	GOA
involved in negative regulation of cell population proliferation	IDA IDA: Inferred from direct assay	14555988	GOA
involved in negative regulation of cell population proliferation	IMP IMP: Inferred from mutant phenotype	11158066	GOA
involved in negative regulation of cell-cell adhesion	IDA IDA: Inferred from direct assay	18593713	GOA
involved in negative regulation of epithelial cell proliferation	IDA IDA: Inferred from direct assay	9950587	GOA
involved in negative regulation of epithelial cell proliferation	IMP IMP: Inferred from mutant phenotype	16943770	GOA
involved in negative regulation of fat cell differentiation	IDA IDA: Inferred from direct assay	15040835	GOA
acts upstream of or within negative regulation of gene expression	IDA IDA: Inferred from direct assay	29529050	GOA
involved in negative regulation of gene expression	IDA IDA: Inferred from direct assay	19913496	GOA
acts upstream of negative regulation of gene expression	IGI IGI: Inferred from genetic interaction	22269326	GOA
involved in negative regulation of gene expression	IGI IGI: Inferred from genetic interaction	22269326	GOA
involved in negative regulation of hyaluronan biosynthetic process	IDA IDA: Inferred from direct assay	17324121	GOA
involved in negative regulation of macrophage cytokine production	IDA IDA: Inferred from direct assay	20875417	GOA
involved in negative regulation of miRNA transcription	IMP IMP: Inferred from mutant phenotype	25605017	GOA
involved in negative regulation of myoblast differentiation	IDA IDA: Inferred from direct assay	9770491	GOA
involved in negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target	IDA IDA: Inferred from direct assay	24586048	GOA
involved in negative regulation of protein localization to plasma membrane	IDA IDA: Inferred from direct assay	21168935	GOA
involved in negative regulation of protein phosphorylation	IDA IDA: Inferred from direct assay	8053900	GOA
involved in negative regulation of skeletal muscle tissue development	IDA IDA: Inferred from direct assay	9770491	GOA
involved in phosphate-containing compound metabolic process	IDA IDA: Inferred from direct assay	10513816	GOA
involved in positive regulation of DNA-templated transcription	IDA IDA: Inferred from direct assay	9389648	GOA
involved in positive regulation of ERK1 and ERK2 cascade	IDA IDA: Inferred from direct assay	25310401	GOA
involved in positive regulation of MAPK cascade	IDA IDA: Inferred from direct assay	26572508	GOA
involved in positive regulation of SMAD protein signal transduction	IDA IDA: Inferred from direct assay	9389648	GOA
involved in positive regulation of SMAD protein signal transduction	IGI IGI: Inferred from genetic interaction	22714950	GOA
involved in positive regulation of SMAD protein signal transduction	IMP IMP: Inferred from mutant phenotype	26908446	GOA
involved in positive regulation of blood vessel endothelial cell migration	IDA IDA: Inferred from direct assay	18555217	GOA
involved in positive regulation of canonical NF-kappaB signal transduction	IMP IMP: Inferred from mutant phenotype	25196641	GOA
involved in positive regulation of canonical Wnt signaling pathway	IDA IDA: Inferred from direct assay	12893825	GOA
acts upstream of positive regulation of canonical Wnt signaling pathway	IMP IMP: Inferred from mutant phenotype	25605017	GOA
involved in positive regulation of cardiac muscle cell differentiation	IDA IDA: Inferred from direct assay	25163461	GOA
involved in positive regulation of cell migration	IDA IDA: Inferred from direct assay	19736306	GOA
involved in positive regulation of cell migration	IMP IMP: Inferred from mutant phenotype	26169693	GOA
involved in positive regulation of cell population proliferation	IDA IDA: Inferred from direct assay	10513816	GOA
involved in positive regulation of cell population proliferation	IMP IMP: Inferred from mutant phenotype	26169693	GOA
involved in positive regulation of chemokine (C-X-C motif) ligand 2 production	IMP IMP: Inferred from mutant phenotype	32141990	GOA
involved in positive regulation of chemotaxis	IDA IDA: Inferred from direct assay	18555217	GOA
involved in positive regulation of collagen biosynthetic process	IDA IDA: Inferred from direct assay	19734317	GOA
involved in positive regulation of collagen biosynthetic process	IGI IGI: Inferred from genetic interaction	22269326	GOA
involved in positive regulation of collagen biosynthetic process	IMP IMP: Inferred from mutant phenotype	11158066	GOA
involved in positive regulation of endothelial cell apoptotic process	IMP IMP: Inferred from mutant phenotype	32141990	GOA
acts upstream of positive regulation of epidermal growth factor receptor signaling pathway	IDA IDA: Inferred from direct assay	18625725	GOA
involved in positive regulation of epithelial to mesenchymal transition	IDA IDA: Inferred from direct assay	17999987	GOA
involved in positive regulation of epithelial to mesenchymal transition	IMP IMP: Inferred from mutant phenotype	21490602	GOA
involved in positive regulation of fibroblast migration	IDA IDA: Inferred from direct assay	18555217	GOA
involved in positive regulation of gene expression	IDA IDA: Inferred from direct assay	18625725	GOA
involved in positive regulation of gene expression	IGI IGI: Inferred from genetic interaction	22269326	GOA
involved in positive regulation of gene expression	IMP IMP: Inferred from mutant phenotype	26169693	GOA
involved in positive regulation of inflammatory response	IMP IMP: Inferred from mutant phenotype	32141990	GOA
involved in positive regulation of interleukin-17 production	IDA IDA: Inferred from direct assay	18453574	GOA
acts upstream of positive regulation of interleukin-6 production	IMP IMP: Inferred from mutant phenotype	25196641	GOA
involved in positive regulation of interleukin-6 production	IMP IMP: Inferred from mutant phenotype	32141990	GOA
acts upstream of or within positive regulation of isotype switching to IgA isotypes	IDA IDA: Inferred from direct assay	14988498	GOA
involved in positive regulation of mesenchymal stem cell proliferation	IGI IGI: Inferred from genetic interaction	22714950	GOA
involved in positive regulation of miRNA transcription	IDA IDA: Inferred from direct assay	26311719	GOA
involved in positive regulation of peptidyl-tyrosine phosphorylation	IDA IDA: Inferred from direct assay	21168935	GOA
involved in positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	IDA IDA: Inferred from direct assay	18625725	GOA
involved in positive regulation of primary miRNA processing	IDA IDA: Inferred from direct assay	18548003	GOA
involved in positive regulation of protein import into nucleus	IDA IDA: Inferred from direct assay	19366691	GOA
involved in positive regulation of protein localization to nucleus	IDA IDA: Inferred from direct assay	26634652	GOA
involved in positive regulation of protein metabolic process	IDA IDA: Inferred from direct assay	15219857	GOA
involved in positive regulation of protein secretion	IDA IDA: Inferred from direct assay	18505915	GOA
involved in positive regulation of protein-containing complex assembly	IDA IDA: Inferred from direct assay	19366691	GOA
involved in positive regulation of receptor signaling pathway via STAT	IDA IDA: Inferred from direct assay	28467929	GOA
involved in positive regulation of smooth muscle cell proliferation	IDA IDA: Inferred from direct assay	28467929	GOA
involved in positive regulation of superoxide anion generation	IDA IDA: Inferred from direct assay	22073128	GOA
involved in positive regulation of transcription by RNA polymerase II	IDA IDA: Inferred from direct assay	12574355	GOA
involved in positive regulation of tumor necrosis factor production	IMP IMP: Inferred from mutant phenotype	32141990	GOA
involved in positive regulation of vascular permeability	IDA IDA: Inferred from direct assay	21168935	GOA
involved in positive regulation of vasculature development	IDA IDA: Inferred from direct assay	27693460	GOA
involved in protein export from nucleus	IDA IDA: Inferred from direct assay	17438144	GOA
involved in receptor catabolic process	IDA IDA: Inferred from direct assay	17878231	GOA
NOT involved in regulation of miRNA transcription	IMP IMP: Inferred from mutant phenotype	18548003	GOA
involved in regulatory T cell differentiation	IDA IDA: Inferred from direct assay	32644293	GOA
involved in response to cholesterol	IDA IDA: Inferred from direct assay	17878231	GOA
involved in response to estradiol	IDA IDA: Inferred from direct assay	18039789	GOA
involved in response to progesterone	IDA IDA: Inferred from direct assay	18039789	GOA
involved in response to wounding	IEP IEP: Inferred from expression pattern	18040277	GOA
involved in salivary gland morphogenesis	IEP IEP: Inferred from expression pattern	18080134	GOA
acts upstream of sprouting angiogenesis	IMP IMP: Inferred from mutant phenotype	31368162	GOA
involved in transforming growth factor beta receptor signaling pathway	IDA IDA: Inferred from direct assay	9389648	GOA
involved in transforming growth factor beta receptor signaling pathway	IGI IGI: Inferred from genetic interaction	22714950	GOA
involved in transforming growth factor beta receptor signaling pathway	IMP IMP: Inferred from mutant phenotype	25196641	GOA

Cellular Component GO Annotation	Evidence	Referencias	Source
located in cell surface	IMP IMP: Inferred from mutant phenotype	19366691	GOA
located in cytoplasm	IDA IDA: Inferred from direct assay	18040277	GOA
located in extracellular space	IDA IDA: Inferred from direct assay	19734317	GOA
colocalizes with microvillus	IDA IDA: Inferred from direct assay	19366691	GOA
located in nucleus	IDA IDA: Inferred from direct assay	18040277	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TGFB1 Protein Structure

TGFb_propeptide

TGF_beta

0
100
200
300
390 a.a.

Protein Preferred Names	Protein Names
transforming growth factor beta-1 proprotein	TGF-beta-1 latency-associated peptide prepro-transforming growth factor beta-1 transforming growth factor beta1

TGFB1 Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Referencias
Intra	TGFB1	P01137	KRTAP10-8	Homo sapiens	P60410	Y2H Prey Pooling	32296183
Intra	TGFB1	P01137	KRTAP10-8	Homo sapiens	P60410	Validated Y2H	32296183
Intra	TGFB1	P01137	KRTAP10-8	Homo sapiens	P60410	Y2H Array	32296183
Intra	TGFB1	P01137	ADAMTSL4	Homo sapiens	Q6UY14-3	Y2H Prey Pooling	32296183
Intra	TGFB1	P01137	ADAMTSL4	Homo sapiens	Q6UY14-3	Validated Y2H	32296183
Intra	TGFB1	P01137	ADAMTSL4	Homo sapiens	Q6UY14-3	Y2H Array	32296183
Intra	TGFB1	P01137	TGFBR1	Homo sapiens	P36897	Crosslink	20856203
Intra	TGFB1	P01137	KRTAP4-11	Homo sapiens	Q9BYQ6	Validated Y2H	32296183
Intra	TGFB1	P01137	KRTAP4-11	Homo sapiens	Q9BYQ6	Y2H Array	32296183
Intra	TGFB1	P01137	KRTAP4-11	Homo sapiens	Q9BYQ6	Y2H Prey Pooling	32296183
Intra	TGFB1	P01137	LTBP1	Homo sapiens	Q14766-1	Pull Down	21677751
Intra	TGFB1	P01137	LTBP1	Homo sapiens	Q14766-1	TEM	21677751
Intra	TGFB1	P01137	LTBP1	Homo sapiens	Q14766-1	GMS	21677751
Intra	TGFB1	P01137	LTBP1	Homo sapiens	Q14766-1	Light Scattering	21677751
Intra	TGFB1	P01137	LCE2B	Homo sapiens	O14633	Y2H Array	32296183
Intra	TGFB1	P01137	LCE2B	Homo sapiens	O14633	Y2H Prey Pooling	32296183
Intra	TGFB1	P01137	LCE1D	Homo sapiens	Q5T752	Y2H Prey Pooling	32296183
Intra	TGFB1	P01137	LCE1D	Homo sapiens	Q5T752	Validated Y2H	32296183
Intra	TGFB1	P01137	LCE1D	Homo sapiens	Q5T752	Y2H Array	32296183
Intra	TGFB1	P01137	KRTAP1-3	Homo sapiens	Q8IUG1	Y2H Array	32296183
Intra	TGFB1	P01137	KRTAP1-3	Homo sapiens	Q8IUG1	Y2H Prey Pooling	32296183
Intra	TGFB1	P01137	KRTAP1-1	Homo sapiens	Q07627	Y2H Prey Pooling	32296183
Intra	TGFB1	P01137	KRTAP1-1	Homo sapiens	Q07627	Validated Y2H	32296183
Intra	TGFB1	P01137	KRTAP1-1	Homo sapiens	Q07627	Y2H Array	32296183
Intra	TGFB1	P01137	LCE1A	Homo sapiens	Q5T7P2	Y2H Prey Pooling	32296183
Intra	TGFB1	P01137	LCE1A	Homo sapiens	Q5T7P2	Validated Y2H	32296183
Intra	TGFB1	P01137	LCE1A	Homo sapiens	Q5T7P2	Y2H Array	32296183
Intra	TGFB1	P01137	LCE2C	Homo sapiens	Q5TA81	Y2H Prey Pooling	32296183
Intra	TGFB1	P01137	LCE2C	Homo sapiens	Q5TA81	Y2H Array	32296183
Intra	TGFB1	P01137	LCE2C	Homo sapiens	Q5TA81	Validated Y2H	32296183
Intra	TGFB1	P01137	LCE3B	Homo sapiens	Q5TA77	Y2H Prey Pooling	32296183
Intra	TGFB1	P01137	LCE3B	Homo sapiens	Q5TA77	Validated Y2H	32296183
Intra	TGFB1	P01137	LCE3B	Homo sapiens	Q5TA77	Y2H Array	32296183
Intra	TGFB1	P01137	FCHO1	Homo sapiens	A0A0C3SFZ9	Y2H Prey Pooling	32296183
Intra	TGFB1	P01137	FCHO1	Homo sapiens	A0A0C3SFZ9	Y2H Array	32296183
Intra	TGFB1	P01137	LCE1C	Homo sapiens	Q5T751	Validated Y2H	32296183
Intra	TGFB1	P01137	LCE1C	Homo sapiens	Q5T751	Y2H Array	32296183
Intra	TGFB1	P01137	LCE1C	Homo sapiens	Q5T751	Y2H Prey Pooling	32296183
Intra	TGFB1	P01137	LRRC32	Homo sapiens	Q14392	Anti Bait CoIP	19651619
Intra	TGFB1	P01137	POU4F2	Homo sapiens	Q12837	Y2H Array	32296183
Intra	TGFB1	P01137	POU4F2	Homo sapiens	Q12837	Validated Y2H	32296183
Intra	TGFB1	P01137	POU4F2	Homo sapiens	Q12837	Y2H Prey Pooling	32296183
Intra	TGFB1	P01137	FSTL1	Homo sapiens	Q12841	SPR	20860622
Intra	TGFB1	P01137	FSTL1	Homo sapiens	Q12841	Competition Binding	20860622
Intra	TGFB1	P01137	THBS1	Homo sapiens	P07996	Solid Phase Assay	15864306
Intra	TGFB1	P01137	DIP2A	Homo sapiens	Q14689	SPR	20860622
Intra	TGFB1	P01137	TNXB	Homo sapiens	P22105	Anti Tag CoIP	35443807
Intra	TGFB1	P01137	ENG	Homo sapiens	P17813	Crosslink	20856203
Intra	TGFB1	P01137	TGFBR3	Homo sapiens	Q03167	Crosslink	20856203
Intra	TGFB1	P01137	TGFBR2	Homo sapiens	P37173	Anti Bait CoIP	35443807
Intra	TGFB1	P01137	TGFBR2	Homo sapiens	P37173	Crosslink	20856203
Intra	TGFB1	P01137	TGFBR2	Homo sapiens	P37173	SPR	20860622
Intra	TGFB1	P01137	CYSRT1	Homo sapiens	A8MQ03	Y2H Prey Pooling	32296183
Intra	TGFB1	P01137	CYSRT1	Homo sapiens	A8MQ03	Y2H Array	32296183
Intra	TGFB1	P01137	P4HB	Homo sapiens	P07237	Y2H Prey Pooling	32296183
Intra	TGFB1	P01137	P4HB	Homo sapiens	P07237	Validated Y2H	32296183
Intra	TGFB1	P01137	P4HB	Homo sapiens	P07237	Y2H Array	32296183
Intra	TGFB1	P01137	LCE3D	Homo sapiens	Q9BYE3	Y2H Array	32296183
Intra	TGFB1	P01137	LCE3D	Homo sapiens	Q9BYE3	Y2H Prey Pooling	32296183
Intra	TGFB1	P01137	LCE3D	Homo sapiens	Q9BYE3	Validated Y2H	32296183
Intra	TGFB1	P01137	PSG1	Homo sapiens	P11464	ELISA	25548275
Intra	TGFB1	P01137	PSG1	Homo sapiens	P11464	SPR	25548275
Intra	TGFB1	P01137	HOXA1	Homo sapiens	P49639	Y2H Prey Pooling	32296183
Intra	TGFB1	P01137	HOXA1	Homo sapiens	P49639	Y2H Array	32296183
Intra	TGFB1	P01137	HOXA1	Homo sapiens	P49639	Validated Y2H	32296183
Intra	TGFB1	P01137	LPXN	Homo sapiens	O60711	Y2H Array	32296183
Intra	TGFB1	P01137	LPXN	Homo sapiens	O60711	Y2H Prey Pooling	32296183
Intra	TGFB1	P01137	CATSPER1	Homo sapiens	Q8NEC5	Y2H Array	32296183
Intra	TGFB1	P01137	CATSPER1	Homo sapiens	Q8NEC5	Y2H Prey Pooling	32296183
Intra	TGFB1	P01137	CATSPER1	Homo sapiens	Q8NEC5	Validated Y2H	32296183
Intra	TGFB1	P01137	MEOX2	Homo sapiens	P50222	Y2H Prey Pooling	25416956
Intra	TGFB1	P01137	APP	Homo sapiens	P05067	Photoaffinity Labelling	2119582
Intra	TGFB1	P01137	LCE3A	Homo sapiens	Q5TA76	Y2H Prey Pooling	32296183
Intra	TGFB1	P01137	LCE3A	Homo sapiens	Q5TA76	Y2H Array	32296183
Intra	TGFB1	P01137	LCE3A	Homo sapiens	Q5TA76	Validated Y2H	32296183
Cross	TGFB1	P01137	TGFBR3	Gallus gallus	Q90998	Crosslink	10092230

Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant TGFB1 Proteins

Referencia número	Nombre del producto	Accession	Pureza
HY-P7118	TGF beta 1/TGFB1 Protein, Human (CHO)	P01137 (A279-S390)	≥ 95%, as determined by reducing SDS-PAGE.
HY-P70236	Latent TGF beta 1/TGFB1 Protein, Human (C33S, HEK293, His)	P01137 (L30-S390, C33S)	≥ 95%, as determined by reducing SDS-PAGE.
HY-P70433	TGF beta 1/TGFB1 LAP Protein, Human (HEK293)	P01137 (L30-R278, C33S)	≥ 95%, as determined by reducing SDS-PAGE.
HY-P70543	TGF beta 1/TGFB1 Protein, Human (HEK293)	P01137 (A279-S390)	≥ 95%, as determined by reducing SDS-PAGE or Bis-Tris PAGE.
HY-P71056	TGF beta 1/TGFB1 Protein, Human (Biotinylated, HEK293, N-Avi)	P01137 (A279-S390)	≥ 95%, as determined by reducing SDS-PAGE.
HY-P70543G	GMP TGF beta 1/TGFB1 Protein, Human (CHO)	P01137 (A279-S390)	≥ 95%, as determined by reducing SDS-PAGE.
HY-P72636	GARP&Latent TGF beta 1 Complex Protein, Human (HEK293, His, Strep)	P01137&Q14392 (L30-S390&H20-N627)	≥ 95%, as determined by reducing SDS-PAGE.
HY-P73426	Latent TGF beta 1/TGFB1 Protein, Human (HEK293, His)	P01137 (L30-S390)	≥ 95%, as determined by reducing SDS-PAGE.
HY-P73616	TGF beta 1/TGFB1 LAP Protein, Human (HEK293, His)	P01137 (L30-R278, C33S)	≥ 95%, as determined by reducing SDS-PAGE.
HY-P78213	Mature TGF beta 1/TGFB1 Protein, Human (Biotinylated, HEK293, Avi)	P01137 (A279-S390)	≥ 95%, as determined by Bis-Tris PAGE.
HY-P77671	GARP (Y137H)&Latent TGF Beta Complex Protein, Human (HEK293, His-Avi)	Q14392 (H20-L628, Y137H)&P01137 (L30-S390)	≥ 95%, as determined by Bis-Tris PAGE.
HY-P77672	GARP (S138G)&Latent TGF Beta Complex Protein, Human (HEK293, His-Avi)	Q14392 (H20-L628, S138G)&P01137 (L30-S390)	≥ 95%, as determined by Bis-Tris PAGE.
HY-P77673	GARP (G139N)&Latent TGF Beta Complex Protein, Human (HEK293, His-Avi)	Q14392 (H20-L628, G139N)&P01137 (L30-S390)	≥ 95%, as determined by Bis-Tris PAGE.
HY-P77674	GARP&Latent TGF Beta Complex Protein, Human (HEK293, His-Avi)	Q14392 (H20-L628)&P01137 (L30-S390)	≥ 95%, as determined by Bis-Tris PAGE.
HY-P77675	GARP&Latent TGF beta Complex Protein, Human (Biotinylated, HEK293, His-Avi)	Q14392 (H20-L628,GARP)&P01137 (L30-S390,Latent TGF bata 1)	≥ 95%, as determined by Bis-Tris PAGE.
HY-P78168	TGF beta 1/TGFB1 LAP Protein, Human (Biotinylated, HEK293, His-Avi)	P01137 (L30-R278, C33S)	≥ 90%, as determined by Bis-Tris PAGE.
HY-P78214	Latent TGF beta 1/TGFB1 Protein, Human (Biotinylated, C33S, HEK293, His-Avi)	P01137 (L30-S390, C33S)	≥ 90%, as determined by Bis-Tris PAGE.
HY-P78668	TGF beta 1/TGFB1 LAP Protein, Human (HEK293, N-His)	P01137/NP_000651.3 (L30-R278, C33S)	≥ 95%, as determined by reducing SDS-PAGE.
HY-P77676	GARP (Mutated)&Latent TGF Beta Complex Protein, Human (HEK293, His-Avi)	Q14392 (H20-L628, Y137H, S138G, G139N)&P01137 (L30-S390)	≥ 95%, as determined by Bis-Tris PAGE.
HY-P700150AF	Animal-Free TGF beta 1/TGFB1 Protein, Human (His)	P01137 (A279-S390)	≥ 95%, as determined by reducing SDS-PAGE.

TGFB1 Antibodies

Referencia número	Nombre del producto	Aplicación	Reactivity
HY-P80521	TGF beta 1 Antibody (YA036)	WB, IHC-P	Human, Mouse, Rat
HY-P85695	TGF beta Antibody (YA5387)	IHC-P, WB	Human, Mouse, Rat
HY-P85823	TGF beta 1 Antibody (YA5515)	IHC-P, WB, ICC/IF, ELISA	Human, Mouse, Rat
HY-P86472	TGF beta 1/TGF beta 3 Antibody (YA6164)	WB, ICC/IF, IP, ELISA	Human, Mouse, Rat
HY-P86476	TGF beta 1 Antibody (YA6168)	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat
HY-P86743	TGF beta 1 Antibody (YA6435)	IHC-P, IHC-F, IF-Tissue	Rat, Mouse
HY-P86743A	TGF beta 1 Antibody (YA6435)(PBS only)	IHC-P, IHC-F, IF-Tissue	Rat, Mouse

Related Diseases

Diseases	Alias
Plantar Fasciitis	Fasciitis, Plantar
Fibromatosis, Gingival, 1	GINGF1 Ggf1 Fibromatosis, Gingival, Hereditary Hgf Hereditary Gingival Fibromatosis Gingf Gingival Fibromatosis, 1 Fibromatosis Gingival, Hereditary, 1 Hgf1 Hereditary Gingival Fibromatosis, 1
Thrombocytopenia	Low Platelet Count Low Platelets Decreased Platelets Platelet Dysfunction Nos
Iga Glomerulonephritis	Iga Nephropathy Glomerulonephritis, Iga Berger'S Iga Or Igg Nephropathy Focal Glomerulonephritis Primary Iga Nephropathy Segmental Glomerulonephritis Berger Disease Berger'S Disease Igan Nephritis, Iga Type Nephropathy Iga Glomerulonephritis Focal Iga Nephropathy, Susceptibility To Primary Immunoglobulin A Nephropathy
Hepatocellular Carcinoma	Liver Cancer Primary Liver Cancer HCC Hepatoma Malignant Neoplasm Of Liver Liver Neoplasms Cancer, Hepatocellular Liver Cell Carcinoma Lcc Hepatoblastoma, Somatic Hepatic Cancer Primary Malignant Neoplasm Of Liver Rare Tumor Of Liver And Intrahepatic Biliary Tract Hepatocellular Carcinoma, Somatic Hepatocellular Carcinoma, Childhood Type, Somatic Hepatocellular Cancer, Somatic Ca Liver - Primary Hepatic Neoplasm Malignant Hepato-Biliary Neoplasm Malignant Neoplasm Of Liver, Not Specified As Primary Or Secondary Malignant Neoplasm Of Liver, Primary Malignant Tumor Of Liver Neoplasm Of Liver Non-Resectable Primary Hepatic Malignant Neoplasm Resectable Malignant Neoplasm Of Liver Resectable Malignant Neoplasm Of The Liver Primary Liver Carcinoma Primary Malignant Liver Neoplasm Primary Cancer Of Liver Primary Tumor Of The Liver Rare Tumor Of Liver And Ibt Hepatocellular Cancer Neoplasm Of The Liver Hepatomas Liver Neoplasm Liver Carcinoma Liver And Intrahepatic Biliary Tract Carcinoma Malignant Hepatobiliary Neoplasm Adult Primary Hepatocellular Carcinoma Hepatoblastoma Carcinoma Of Liver Malignant Liver Tumour Malignant Hepatic Tumour
Thrombophlebitis	Phlebitis And Thrombophlebitis Of Superficial Vessels Of Lower Extremities Superficial Thrombophlebitis Of Leg Thrombophlebitis Of A Superficial Leg Vein Thrombophlebitis Of Superficial Veins Of Lower Extremity
Muscular Dystrophy	Muscular Dystrophies Congenital Md Congenital Muscular Dystrophy Cmd Mdc Dystrophy, Muscular Gower'S Muscular Dystrophy Progressive Musclular Dystrophy Pseudohypertrophic Atrophy Pseudohypertrophic Muscle Paralysis Pseudohypertrophic Muscular Atrophy Pseudohypertrophic Muscular Dystrophy Pseudohypertrophic Paralysis Pseudomuscular Hypertrophy
Urethral Stricture	Ankylurethria Urethral Stenosis Urethral Contracture Urethral Obstruction Meatal Stenosis Nos Constriction Of Urethra Contraction Of Urethra Stricture Of Urinary Meatus Urethral Obliteration Urethral Narrowing Pinpoint Meatus Pinhole Meatus Nos Urethral Occlusion
Inflammatory Bowel Disease, Immunodeficiency, And Encephalopathy	IBDIMDE Infantile Inflammatory Bowel Disease With Neurological Involvement
Osteonecrosis Of The Jaw
Vitreoretinopathy, Neovascular Inflammatory	Proliferative Vitreoretinopathy Adniv Autosomal Dominant Neovascular Inflammatory Vitreoretinopathy VRNI Pvr Neovascular Inflammatory Vitreoretinopathy Vitreoretinopathy, Neovascular Inflammatory, Autosomal Dominant Retinitis Proliferans Neovascular Inflammatory Vitreoretinopathy Autosomal Dominant Vitreoretinopathy Proliferative Vitreoretinopathy, Proliferative Proliferative Vitreo-Retinopathy
Malaria	Malaria, Susceptibility To Malaria, Resistance To Malaria, Cerebral Cerebral Malaria Malaria, Severe, Susceptibility To Malaria, Severe, Resistance To Malaria, Cerebral, Susceptibility To Induced Malaria Malaria, Vivax, Protection Against Malaria, Severe Malaria, Cerebral, Reduced Risk Of Malaria, Protection Against Resistance To Malaria Due To G6pd Deficiency Malaria Due To G6pd Deficiency Malarial Encephalitis CM Malaria Cerebral Susceptibility To Malaria Acute Pernicious Fever Aestivo-Autumnal Fever Aestivo Autumnal Malaria Chagres Fever Continued Malaria Fever Estivo-Autumnal Fever Estivo-Autumnal Malaria Estivo-Autumnal Malarial Fever Falciparum Fever Malignant Tertian Fever Malignant Tertian Malaria Pernicious Intermittent Fever Pernicious Malaria Quotidian Malaria Subtertian Fever Subtertian Malaria Fever Subtertian Malignant Tertian Malaria Tropical Malaria Algid Malaria Bilious Haemoglobinuric Fever Black Water Fever Blackwater Fever Malarial Blackwater Fever Severe Malarial Falciparum West African Fever Malarial Haematinuria Haemoglobinuric Fever Haemoglobinuric Malaria Severe Plasmodium Falciparum Malaria Malarial Haemoglobinuria Malarial Haematuria Falciparum Malaria [Malignant Tertian] Malaria Tropica Malarial Shock Chagres Virus Disease Malignant Malaria Mtm - [Malignant Tertian Malaria] Tm -[Malignant Tertian Malaria] Panama Fever St - [Subtertian Malaria] Malarial Quotidian Benign Tertian Malaria Tertian Ague Vivax Fever Plasmodium Vivax Malaria Nos Btm - [Benign Tertian Malaria] Bt - [Benign Tertian Malaria] Vivax Malaria Benign Tertian Vivax Malaria Tertian Malaria Quartan Malaria Quartan Ague Quartan Fever Plasmodium Malariae Malaria Nos Quartan Malarial Malaria By Plasmodium Malariae Malariae Malaria Ovale Tertian Malaria Plasmodium Ovale Fever Malaria Fever By Plasmodium Ovale Ovale Malaria Malaria By Plasmodium Ovale Malarial Ovale Marsh Fever Remittent Congestive Fever Coastal Fever Remittent Gastric Fever Miasmatic Fever Congestive Remittent Fever Intermittent Fever Jungle Fever Paludism Cameroon Fever Ague Corsican Fever Intermittent Bilious Fever Disease Due To Plasmodiidae Malarial Fever Plasmodiosis Remittent Fever Roman Fever Malaria Fever Nos Malaria Nos Paludal Fever Clinically Diagnosed Malaria Clinically Diagnosed Malaria Without Parasitological Confirmation Congestive Fever Malarial Cachexia Marsh Cachexia Paludal Cachexia Recurrent Malaria Remittent Malaria
Camurati-Engelmann Disease	Progressive Diaphyseal Dysplasia Ced Engelmann Disease Diaphyseal Dysplasia 1, Progressive Pdd Diaphyseal Dysplasia Dpd1 Camurati-Engelmann Syndrome CAEND Engelman'S Disease Diaphyseal Hyperostosis Diaphyseal Osteosclerosis
Ankylosis
Cataract	Cataracts Cat - [Cataract] Cataract Form Lens Opacity Lens Opacities
Interstitial Lung Disease	Ild Lung Diseases, Interstitial Lung Diseases Interstitial Interstitial Lung Diseases
Hereditary Hemorrhagic Telangiectasia	Rendu-Osler-Weber Disease Hht Osler-Weber-Rendu Disease Telangiectasia, Hereditary Hemorrhagic Osler Hemorrhagic Telangiectasia Syndrome Orw Disease Osler Weber Rendu Syndrome Osler-Rendu-Weber Disease Osler-Weber-Rendu Syndrome Rendu-Osler Disease Telangiectasia Hereditary Hemorrhagic Telangiectasia Hemorrhagic, Hereditary Hht - [Hereditary Haemorrhagic Telangiectasia] Osler Haemorrhagic Telangiectasia Syndrome
Keratoconus	Kc Conical Cornea Noninflammatory Corneal Thining Bulging Cornea Cornea Conical Acquired Conus Of Cornea
Liver Cirrhosis	Cirrhosis Cirrhosis Of Liver CIRRH Cryptogenic Cirrhosis Cirrhosis, Cryptogenic Cirrhosis Nos
Fibromuscular Dysplasia
Colorectal Cancer	Colon Cancer Colorectal Carcinoma Colon Carcinoma Colorectal Cancer, Susceptibility To Carcinoma Of Colon CRC Colorectal Cancer With Chromosomal Instability, Somatic Colon Cancer, Somatic Colon Cancer, Susceptibility To Colonic Neoplasms Colorectal Neoplasms Colorectal Cancer, Somatic Colon Cancer, Advanced, Somatic Colonic Carcinoma Colorectal Carcinomas Colon Cancers Colorectal Cancers Cancer, Colorectal, Somatic Cancer, Colon Cancer, Colorectal, Susceptibility To Colorectal Neoplasm Colonic Neoplasm Malignant Tumor Of Colon
Encephalopathy	Brain Diseases Encephalopathies Toxic Encephalopathy Toxic Brain Fever Toxic Brain Inflammation Toxic Brain Stem Inflammation Toxic Cerebral Fever Toxic Cerebrospinal Fever Toxic Cerebrospinal Inflammation Encephalopathy Nec Encephalopathy Nos Encephalopathy Disease Encephalopathy Syndrome
Penile Disease	Penile Diseases
Hypertrophic Scars	Scars Hypertrophic Hypertrophic Scarring
Impotence	Erectile Dysfunction Sexual Impotence Erectile Dysfunction Adverse Event
Stiff Skin Syndrome	SSKS Stiff Skin
Geleophysic Dysplasia	Geleophysic Dwarfism Gphysd
Gastric Cancer	Stomach Cancer Stomach Carcinoma Gastric Carcinoma Gastric Cancer, Somatic Gastric Neoplasm Carcinoma Of Stomach Stomach Neoplasms Malignant Neoplasm Of Stomach Gastric Cancer Risk After H. Pylori Infection Cancer Of The Stomach Adult Stomach Cancer Adult Stomach Carcinoma GASC Gastric Cancer Intestinal Gastric Cancers Gastric Carcinomas Cancer, Gastric Stomach Neoplasm Malignant Neoplasm Of Body Of Stomach Malignant Tumor Of Lesser Curve Of Stomach Gastrocarcinoma Of Unspecified Site Leather Bottle Stomach Carcinoma Of Fundus Of Stomach Cancer Of Fundus Of Stomach Primary Malignant Neoplasm Of Body Of Stomach Cancer Of Body Of Stomach Primary Malignant Neoplasm Of Pyloric Antrum Pyloric Antrum Cancer Malignant Tumour Of Stomach
Carpal Tunnel Syndrome	Cts Carpal Tunnel Syndrome, Familial Carpal Tunnel Syndrome 1 CTS1 Amyotrophy, Thenar, Of Carpal Origin Carpal Tunnel Median Neuropathy Cts - Carpal Tunnel Syndrome Median Nerve Entrapment Carpal Canal Carpal Tunnel Compression Neuropathy, Carpal Tunnel Distal Median Nerve Compression Distal Median Nerve Entrapment Entrapment Neuropathy, Carpal Tunnel Median Neuropathy, Carpal Tunnel Median Neuropathy Carpal Tunnel Thenar Amyotrophy Of Crapal Origin
Pulmonary Hypertension	Primary Pulmonary Hypertension Hypertension Pulmonary Hypertension, Pulmonary Idiopathic Pulmonary Hypertension Idiopathic Pulmonary Arterial Hypertension Pulmonary Htn - [Hypertension]
Inflammatory Bowel Disease 25, Autosomal Recessive	Immune Dysregulation-Inflammatory Bowel Disease-Arthritis-Recurrent Infections Syndrome IBD25 Inflammatory Bowel Disease 25, Early Onset, Autosomal Recessive Il10-Related Early-Onset Ibd Il10-Related Early-Onset Inflammatory Bowel Disease Inflammatory Bowel Disease, Early-Onset, Autosomal Recessive Autosomal Recessive Early-Onset Inflammatory Bowel Disease Autosomal Recessive Early-Onset Ibd Early-Onset Autosomal Recessive Inflammatory Bowel Disease Bowel Disease, Inflammatory, Type 25, Autosomal Recessive
Gastroesophageal Reflux	Gastroesophageal Reflux Disease Gerd GER Gastroesophageal Reflux, Pediatric Acid Reflux Gastresophageal Reflux Gastro-Esophageal Reflux Gerd - Gastro-Esophageal Reflux Disease
Prostate Cancer	Prostate Carcinoma Prostate Cancer, Familial Prostate Neoplasm Prostate Cancer, Somatic Prostate Cancer, Susceptibility To Prostatic Cancer Prostatic Neoplasms Hereditary Prostate Cancer Prostatic Neoplasm Cancer Of Prostate Carcinoma Of Prostate Familial Prostate Cancer Familial Prostate Carcinoma Malignant Tumor Of Prostate Malignant Neoplasm Of Prostate Prostate Cancer, Familial, Susceptibility To Malignant Tumor Of The Prostate Ngp - New Growth Of Prostate Tumor Of The Prostate Prostate Cancer, Hereditary Cancer Of The Prostate Malignant Neoplasm Of The Prostate Prostatic Carcinoma PC Prca Cancer, Prostate Malignant Prostatic Tumour Malignant Tumour Of Prostate Primary Prostate Cancer Primary Malignant Neoplasm Of Prostate Prostate Gland Cancer
Microvascular Complications Of Diabetes 3	Diabetic Nephropathy Microvascular Complications Of Diabetes, Susceptibility To, 3 MVCD3 Nephropathy, Diabetic Nephropathy, Diabetic, Susceptibility To End-Stage Renal Disease, Diabetic End-Stage Renal Disease, Diabetic, Susceptibility To Diabetic End-Stage Renal Disease Diabetic Nephropathies
Biliary Atresia	Congenital Biliary Atresia Isolated Biliary Atresia Isolated Atresia Of Bile Ducts Non-Syndromic Biliary Atresia Atresia Of Bile Duct Biliary Atresia, Congenital Atresia Of Bile Ducts Bile Duct Atresia Congenital Bile Duct Atresia Ba - [Biliary Atresia] Impervious Bile Duct Atresia Of Common Duct Biliary Duct Atresia Bile Ductal Atresia Cystic Duct Atresia
Cutis Laxa	Generalized Elastolysis Loose Skin Dermatolysis Dermatomegaly Cutis Laxa Syndrome
Patellar Tendinitis	Patellar Tendonitis
Ureteral Obstruction
Osteonecrosis	Bone Necrosis Avascular Necrosis Of Bone Aseptic Necrosis Necrosis Of Bone Nos Aseptic Osteonecrosis Aseptic Necrosis Of Bone, Site Unspecified Aseptic Or Avascular Bone Necrosis Aseptic Necrosis Of Bone Necrotic Bone Necrotizing Bone Spontaneous Osteonecrosis Osteoradionecrosis
Eosinophilia-Myalgia Syndrome	Eosinophilia Myalgia Syndrome Ems L-Tryptophan Induced Ems Severe Muscle Pain And Abnormally High Eosinophils Syndrome With Inflammatory And Autoimmune Components That Affect The Skin, Fascia, Muscle, Nerve, Blood Vessels, Lung, And Heart
Thyroid Gland Anaplastic Carcinoma	Anaplastic Thyroid Carcinoma Anaplastic Thyroid Cancer Thyroid Cancer, Anaplastic Thyroid Carcinoma, Anaplastic Thyroid Carcinoma Anaplastic
Adenocarcinoma	Adenocarcinomas Adenoacanthoma Of Unspecified Site Adenocarcinoid Of Unspecified Site Adenocarcinoid Tumour Of Unspecified Site Adenocarcinoma And Carcinoid Combined Of Unspecified Site Adenocarcinoma Nos
Osteogenic Sarcoma	Osteosarcoma OSRC Osteosarcoma, Somatic Neoplasms, Bone Tissue Bone Tissue Neoplasm Osteoid Sarcoma Skeletal Sarcoma Osteosarcoma Of Bone Bone Sarcoma
Hepatitis	Chronic Hepatitis Chronic Persistent Hepatitis Acute Hepatitis Hepatitis, Chronic Acute And Subacute Liver Necrosis Acute/Subac. Necrosis Of Liver Animal Hepatitis Hepatitis Chronic Hepatitis A Hepatitis, Animal Hepatitis Due To Toxoplasmosis Hepatitis In Toxoplasmosis Toxoplasmal Hepatitis Chronic Hepatitis, Unspecified Chronic Active Hepatitis Nec Other Specified Chronic Hepatitis Chronic Persistent Hepatitis Nec Chronic Lobular Hepatitis Nec
Focal Segmental Glomerulosclerosis	Familial Idiopathic Steroid-Resistant Nephrotic Syndrome Focal Glomerulosclerosis Fsgs Segmental Glomerulosclerosis Glomerulosclerosis, Focal Segmental Fgs Focal Glomerular Sclerosis Familial Idiopathic Nephrotic Syndrome Focal Sclerosis With Hyalinosis Glomerulosclerosis, Focal Glomerulosclerosis Focal Glomerulosclerosis, Segmental, Focal Focal Segmental Glomerulosclerosis, Not Otherwise Specified
Nervous System Disease	Abnormality Of The Nervous System Nervous System Diseases Nervous System Disorder
Esophagitis	Acute Esophagitis
Interstitial Lung Disease 2	Idiopathic Pulmonary Fibrosis Ipf Fibrocystic Pulmonary Dysplasia Pulmonary Fibrosis, Idiopathic Pulmonary Fibrosis, Idiopathic, Susceptibility To ILD2 Idiopathic Pulmonary Fibrosis, Familial Fibrosing Alveolitis, Cryptogenic Uip Cryptogenic Fibrosing Alveolitis Fibrosing Alveolitis Interstitial Pneumonitis, Usual Familial Idiopathic Pulmonary Fibrosis Idiopathic Fibrosing Alveolitis, Chronic Form Usual Interstitial Pneumonia Fibrosing Alveolitis Cryptogenic Hamman-Rich Disease Idiopathic Pulmonary Fibrosis Familial Interstitial Pneumonitis Usual Fibrosis Idiopathic Pulmonary Fibrosis, Pulmonary, Idiopathic Hamman-Rich Syndrome Chronic Idiopathic Pulmonary Fibrosis Acute Interstitial Pneumonia Interstitial Pulmonary Fibrosis Ipf - [Idiopathic Pulmonary Fibrosis] Idiopathic Lung Fibrosis Fibrosing Lung Disease Pulmonary Fibrosis Nos Fibrosing Pneumonitis
Systemic Lupus Erythematosus	Lupus Nephritis SLE Disseminated Lupus Erythematosus Systemic Lupus Erythematosus, Susceptibility To Lupus Erythematosus, Systemic Lupus Nephritis, Susceptibility To Libman-Sacks Disease Systemic Lupus Erythematosus Susceptibility To Sle - Lupus Erythematosus, Systemic Le Syndrome Lupus Lupus Erythematosus Systemic Lupus Erythematosus, Systemic, Susceptibility To Lupus Vulgaris Lupus Erythematosus, Discoid Lupus Erythematosus Systemic Lupus Erythematosus Nos Sle - [Systemic Lupus Erythematosus]
Ulcerative Colitis	Colitis Gravis Left Sided Ulcerative Colitis Left-Sided Ulcerative Colitis Idiopathic Proctocolitis Inflammatory Bowel Disease, Ulcerative Colitis Type Uc Colitis Ulcerative Colitis, Ulcerative Chronic Left-Sided Ulcerative Colitis Uc - [Ulcerative Colitis] Chronic Ulcerative Enteritis Mucosal Proctocolitis Ulcerative Mucosal Proctocolitis Left Hemicolitis
Nephrosclerosis	Renal Sclerosis
Pulmonary Disease, Chronic Obstructive	Chronic Obstructive Pulmonary Disease COPD Pulmonary Disease, Chronic Obstructive, Severe Early-Onset Chronic Obstructive Lung Disease Chronic Obstructive Airway Disease Pulmonary Disease, Chronic Obstructive, Susceptibility To Cold Severe Early-Onset Chronic Obstructive Pulmonary Disease Pulmonary Disease Chronic Obstructive Pulmonary Disease, Obstructive, Chronic, Susceptibility To Chronic Obstructive Pulmonary Disease Of Horses Common Cold Upper Respiratory Infections Copd - [Chronic Obstructive Pulmonary Disease] Coad - [Chronic Obstructive Airways Disease] Cold - [Chronic Obstructive Lung Disease] Chronic Airway Disease Nos Chronic Airways Limitation, Unspecified Chronic Obstructed Airway, Unspecified Chronic Obstructive Airway Disease, Unspecified Chronic Obstructive Airway, Unspecified Obstructive Lung Disease Nos Chronic Obstructive Lung Disease Nos Chronic Obstructive Lung Nos Obstructive Pulmonary Disease Nos Exacerbation Copd Nos Acute Exacerbation Copd
Microphthalmia	Microphthalmos Isolated Anophthalmia-Microphthalmia Syndrome Isolated Microphthalmia-Anophthalmia-Coloboma Simple Microphthalmos Clinical Anophthalmia Isolated Anophthalmia - Microphthalmia Isolated Pure Microphthalmia Mac Spectrum Microphthalmia-Anophthalmia-Coloboma Spectrum Primitive Anophthalmia Globe Of Eye Small Small Eyeball Hypoplasia Of Eye Isolated Nanophthalmos Rudimentary Eye Dysplasia Of Eye
Keloid Disorder	Keloid Cheloid Keloid Scar Non-Surgical Keloid
Gingival Fibromatosis	Hereditary Gingival Fibromatosis Hereditary Gingival Hyperplasia Autosomal Dominant Gingival Fibromatosis Autosomal Dominant Gingival Hyperplasia Fibromatosis, Gingival, Hereditary Fibromatosis, Gingival
Trachoma	Trachoma Dubium Active Stage Trachoma Trachoma, Active Stage Trachoma, Initial Stage Egyptian Ophthalmia Trachoma Pannus Marginal Corneal Pannus Trachomatous Pannus
Marfan Syndrome	MFS Mfs1 Marfan'S Syndrome Marfan Syndrome Type 1 Marfan Syndrome, Type I Mass Phenotype Contractural Arachnodactyly Mass Syndrome Octd Overlap Connective Tissue Disease Marfanoid Hypermobility Syndrome Marfan Disease
Bronchiolitis Obliterans	Bronchiolitis Fibrosa Obliterans Obliterative Bronchiolitis Bronchiolitis Exudativa Bronchiolitis, Exudative
Peyronie'S Disease	Induratio Penis Plastica Peyronie Disease Peyronies Disease Peyronie'S Fibromatosis Penile Induration Balanitis Xerotica Obliterans
Rheumatic Heart Disease	Rheumatic Carditis Rheumatic Congestive Heart Failure Congestive Rheumatic Heart Failure Rheumatic Heart Failure RHD Rheumatic Fever Inactive Or Quiescent With Heart Disease Rheumatic Fever Inactive Or Quiescent With Carditis Organ Rheumatic Heart Disease Organic Rheumatic Heart Disease Inactive Rheumatic Heart Disease Rheumatic Heart Rheumatic Fever Inactive Or Quiescent With Pancarditis Rhd - [Rheumatic Heart Disease] Rheumatic Cardiac Hypertrophy Rheumatic Fever Inactive Or Quiescent With Cardiac Hypertrophy Rheumatic Pancarditis Inactive Rhd - [Rheumatic Heart Disease] Rheumatic Nonischaemic Cardiopathy
Intrahepatic Gall Duct Cancer	Malignant Neoplasm Of Intrahepatic Bile Ducts Malignant Neoplasm Of Intrahepatic Gall Duct Ca Intrahepatic Bile Ducts Malignant Neoplasm Of Intrahepatic Biliary Passages Intrahepatic Bile Duct Carcinoma
Van Buchem Disease	Hyperostosis Corticalis Generalisata Hyperphosphatasemia Tarda VBCH Sost-Related Sclerosing Bone Dysplasia Endosteal Hyperostosis Autosomal Recessive Sclerosteosis Endosteal Hyperostosis, Autosomal Recessive Hyperotosis Corticalis Generalisata Familiaris Sost Sclerosing Bone Dysplasia Smith-Lemli-Opitz Syndrome
Prostatitis
Facial Paralysis	Facial Palsy Bell Palsy
Neuroma
Gingival Overgrowth	Gingival Enlargement Gingival Hyperplasia Gingival Bulge Gingival Enlargement Nos Gingival Hypertrophy Gum Hypertrophy Hyperplasia Gum Gingival Thickening Hyperplasia Of Gingiva Hypertrophy Of Gingiva Hypertrophy Of Mucous Membrane Of Gums
Laryngitis	Acute Laryngitis
Mucositis	Inflammatory Disease Of Mucous Membrane Gastrointestinal Mucositis
Toxoplasmosis	Disseminated Toxoplasmosis Multisystemic Disseminated Toxoplasmosis Acquired Toxoplasmosis Toxoplasmosis Disease Or Disorder Infection By Toxoplasma Gondii Toxoplasmal Toxoplasma
Hydronephrosis	Stricture Of Ureteropelvic Junction With Hydronephrosis Hydronephrosis With Ureteral Stricture, Not Elsewhere Classified
Insulin-Like Growth Factor I	Insulin-Like Growth Factor I Deficiency IGF1 DEFICIENCY Insulin-Like Growth Factor I, Resistance To Growth Retardation With Deafness And Mental Retardation Due To Igf1 Deficiency Growth Delay Due To Insulin-Like Growth Factor Type 1 Deficiency Growth Delay Due To Insulin-Like Growth Factor I Resistance IGF1RES Igf-I Resistance Growth Retardation With Sensorineural Deafness And Mental Retardation Somatomedin, End-Organ Insensitivity To Somatomedin-C Somatomedin-C, Resistance To Insulin-Like Growth Factor 1 Resistance To Igf-1 Resistance Somatomedin End-Organ Insensitivity To Somatomedin-C Resistance To Growth Delay-Deafness-Intellectual Disability Syndrome Growth Delay-Hearing Loss-Intellectual Disability Syndrome Igf-1 Deficiency Primary Insulin-Like Growth Factor Deficiency Resistance To Igf-1 Insulin-Like Growth Factor 1 Resistance End-Organ Insensitivity To Somatomedin Igf1 Resistance Resistance To Insulin-Like Growth Factor I Resistance To Somatomedin-C Insulin-Like Growth Factor 1, Resistance To
Cystic Fibrosis	Mucoviscidosis CF Pseudomonas Aeruginosa, Susceptibility To Chronic Infection By, In Cystic Fibrosis Pseudomonas Aeruginosa Chronic Infection By, In Cystic Fibrosis Cystic Fibrosis Lung Disease, Modifier Of Cystic Fibrosis Of Pancreas Fibrocystic Disease Of Pancreas Cf - [Cystic Fibrosis] Cystic Fibrosis Nos Fibrocystic Disease Fibrocystic Disease Of The Pancreas Mucoviscidosis Of Pancreas Nonproliferative Fibrocystic Disease Pancreatic Cystic Fibrosis
Retinal Detachment	Retinal Detachments Rhegmatogenous Retinal Detachment Ruptured Retina With Detachment Retinal Hole With Detachment
Epicondylitis	Tennis Elbow Lateral Epicondylitis Golfer'S Elbow Medial Epicondylitis Andrel Epicondylitis Archer'S Elbow Hockey Elbow Shooter'S Elbow
Myelofibrosis	Primary Myelofibrosis Agnogenic Myeloid Metaplasia Idiopathic Myelofibrosis Myeloid Metaplasia Myelofibrosis With Myeloid Metaplasia Osteomyelofibrosis Megakaryocytic Myelosclerosis Myelosclerosis Chronic Idiopathic Myelofibrosis Myelofibrosis, Idiopathic Myelofibrosis With Myeloid Metaplasia, Somatic Myelofibrosis, Somatic Aleukemic Myelosis Bone Marrow Fibrosis MYELOF MMM Agnogenic Myeloid Metaplasia With Myelofibrosis Ammm Myelosclerosis With Myeloid Metaplasia Myelofibrosis Nos
Brucellosis	Mediterranean Fever Malta Fever Undulant Fever Gibraltar Fever Bang'S Disease Maltese Fever Cyprus Fever Rock Fever Brucellosis Infection Brucella Infection
Myocardial Infarction	Heart Attack Myocardial Infarction, Susceptibility To Myocardial Infarction 1 Myocardial Infarction, Protection Against Myocardial Infarction, Decreased Susceptibility To Myocardial Infarction, Decreased Myocardial Infarct MCI1 Premature Myocardial Infarction Myocardial Infarction, Susceptibility To, Type 1
Giardiasis	Beaver Feaver Infection By Giardia Lamblia Lambliasis Giardia Lamblia Dysentery Giardial Diarrhoea Lamblia Dysentery Giardia Duodenalis Dysentery Giardia Intestinalis Dysentery
Prolactinoma	Prolactin-Producing Pituitary Gland Adenoma Prolactin-Secreting Pituitary Adenoma Forbes-Albright Syndrome Lactotroph Adenoma Prl-Secreting Pituitary Adenoma Prloma Pituitary Lactotrophic Adenoma Familial Prolactinoma Pituitary Adenoma, Prolactin-Secreting Prolactinoma Of Pituitary Gland PSPA
Silicosis	Silicotuberculosis Acute Silicosis Chronic Silicosis Pneumoconiosis Due To Silicates Silica Pneumoconiosis Silicotic Fibrosis Of Lung Accelerated Silicosis Experimental Silicosis
Osteoarthritis	Osteoarthrosis Degenerative Joint Disease Hypertrophic Arthritis Arthropathy Degenerative Polyarthritis Degenerative Arthritis Osteoarthrosis And Allied Disorder Arthritis, Degenerative Oa Osteoarthritis Deformans Osteoarthrosis Deformans Kashin-Beck Disease
Exophthalmos	Proptosis
Hepatitis C	Chronic Hepatitis C Hepatitis C Infection Hepatitis Nona Nonb Nanbh Viral Hepatitis C Hepatitis C Chronic Hepatitis C, Chronic Chronic Type C Viral Hepatitis Chronic Hcv - [Hepatitis C Virus] Infection Hepatitis C Nos Hepatitis C Infection Nos Hepatitis C-Related Cirrhosis Type C Viral Hepatitis Hep C Nos
Pelvic Organ Prolapse	Rectal Prolapse Pelvic Organ Prolapse, Susceptibility To Pelvic Organ Prolapse, Susceptibility To, 1 Prolapse Of Vagina And Rectum Vaginal Prolapse Pelvic Organ Prolapse 1 Procidentia, Rectum Prolapse Of Rectal Mucosa Procidentia Of Rectum Rectal Mucosa Prolapse Rectum Prolapse Procidentia Rectum Rp - [Rectal Prolapse] Male Proctocele Male Rectocele Proctoptosis Female Genital Prolapse Female Prolapse Incompetence Of Pelvic Fundus Relaxation Of Perineum Deficiency Of Perineum
Inflammatory Bowel Disease	Inflammatory Bowel Diseases Bowel Disease, Inflammatory
Tracheal Stenosis	Stenosis Of Trachea
Beckwith-Wiedemann Syndrome	Wiedemann-Beckwith Syndrome BWS Exomphalos-Macroglossia-Gigantism Syndrome Emg Syndrome Beckwith-Wiedemann Syndrome Due To Cdkn1c Mutation Emg Abnormality Wbs Exomphalos Macroglossia Gigantism Syndrome Beckwith-Wiedemann Syndrome Due To Nsd1 Mutation Macroglossia Exomphalos Gigantism
Asthma	Chronic Obstructive Asthma Asthma, Diminished Response To Antileukotriene Treatment In Bronchial Hyperreactivity Asthma, Susceptibility To Asthma, Bronchial Asthma, Protection Against Asthma, Nocturnal, Susceptibility To Nocturnal Asthma Asthma-Related Traits Asthma-Related Traits, Susceptibility To Asthma, Nocturnal Chronic Obstructive Asthma With Acute Exacerbation Chronic Obstructive Asthma With Status Asthmaticus Exercise Induced Asthma Exercise-Induced Asthma Bronchial Asthma Asthma, Exercise-Induced Idiosyncratic Asthma Unspecified Asthma With Acute Exacerbation Asthma, Unspecified, With Stated Status Asthmaticus Status Asthmaticus Nos Acute Severe Asthma Acute Severe Bronchial Asthma Status Asthma Status Post Asthmaticus
Pancreatic Cancer	Pancreatic Carcinoma Familial Pancreatic Carcinoma Pancreatic Neoplasm Carcinoma Of Pancreas Pancreatic Carcinoma, Familial Malignant Neoplasm Of Pancreas Pancreatic Acinar Carcinoma Pancreatic Tumor Familial Pancreatic Cancer Neoplasm Of The Pancreas Pancreatic Carcinoma, Somatic Pancreatic Cancer, Somatic Ca Body Of Pancreas Ca Head Of Pancreas Ca Tail Of Pancreas Malignant Neoplasm Of Body Of Pancreas Malignant Neoplasm Of Head Of Pancreas Malignant Neoplasm Of Tail Of Pancreas Pancreas Neoplasm Exocrine Cancer Exocrine Pancreas Carcinoma Hereditary Pancreatic Cancer Hereditary Pancreatic Carcinoma PNCA Cancer Of The Pancreas Pancreatic Cancer, Susceptibility To Carcinoma Of Head Of Pancreas Pancreatic Neoplasms Pancreatic Tumors Cancer, Pancreatic Cancer Of Pancreas Mixed Islet Cell With Exocrine Carcinoma Of Unspecified Site
Hydrocephalus	Hydrocephalus, Nonsyndromic, Autosomal Recessive Hydrocephalus, X-Linked Hydrocephalus Adverse Event Hydrocephaly Nos
Strongyloidiasis	Disseminated Strongyloidiasis Anguilluliasis Anguillulosis Infection By Strongyloides Threadworm Infection Enterobiasis
Diarrhea	Diarrhoea Diarrhea Of Presumed Infectious Origin
Lung Disease	Lung Diseases Disorder Of Lung Abnormality Of The Lung
Huntington Disease	Huntington'S Disease Huntington Chorea HD Huntington'S Chorea Huntington Chronic Progressive Hereditary Chorea Juvenile Huntington Disease Chronic Progressive Chorea Chronic Progressive Hereditary Chorea Hc - [Huntington Chorea] Hereditary Chorea Progressive Hereditary Chorea
Corneal Dystrophy
Clonorchiasis	Oriental Liver Fluke Disease Clonorchis Liver Infection Clonorchiosis Chinese Liver Fluke Disease Hepatic Distomiasis Due To Clonorchis Sinensis Infection Due To Clonorchis Sinensis Hepatic Distomiasis Hepatic Distomatosis Chinese Liver Fluke Disorder Oriental Liver Fluke Disorder Clonorchis Infestation Chinese Liver Fluke Infestation Liver Fluke Disease Due To Clonorchis Sinensis Oriental Liver Fluke Infestation
Squamous Cell Carcinoma, Head And Neck	Squamous Cell Carcinoma Of The Head And Neck HNSCC Head And Neck Squamous Cell Carcinoma Head And Neck Cancer Squamous Cell Carcinoma Of Lip Squamous Cell Carcinoma, Head And Neck, Somatic Carcinoma Of The Head And Neck Squamous Cell Carcinomas Of Head And Neck Scchn Squamous Cell Carcinoma Of The Hypopharynx Squamous Cell Carcinoma Of The Oropharynx Squamous Cell Carcinoma Of Salivary Glands Squamous Cell Carcinoma Of The Nasal Cavity And Paranasal Sinuses Squamous Cell Carcinoma Of The Nasal Cavity And Sinuses Squamous Cell Carcinoma Of The Oral Cavity Squamous Cell Carcinoma Of The Lip Carcinoma, Squamous Cell Of Head And Neck Lip Squamous Cell Carcinoma Cancer, Head/Neck Carcinoma, Squamous Cell, Head And Neck Salivary Gland Squamous Cell Carcinoma Cancer Of Head And Neck Squamous Cell Carcinoma Of Oropharynx Nos
Cholecystolithiasis
Conjunctival Vascular Disease	Vascular Abnormalities Of Conjunctiva Conjunctival Vascular Abnormality Vascular Abnormality Of Conjunctiva
Autism Spectrum Disorder	Asd Autism Spectrum Disorders Autistic Continuum Pervasive Developmental Disorder Pervasive Development Disorder Autistic Behavior Autistic Disorder Autistic Autistic Disorder Of Childhood Onset Infantile Autism Childhood Autism Kanner Syndrome Pervasive Developmental Delay Nos Pervasive Developmental Disorder, Not Otherwise Specified
Breast Cancer	Breast Carcinoma Breast Cancer, Familial Malignant Neoplasm Of Breast Male Breast Cancer Breast Cancer, Susceptibility To Breast Cancer, Early-Onset Malignant Tumor Of Breast Carcinoma Of Male Breast Breast Cancer, Invasive Ductal Breast Cancer, Protection Against Breast Cancer, Somatic Breast Cancer, Male Breast Cancer, Lobular, Somatic Breast Tumor Mammary Cancer Mammary Tumor Malignant Neoplasm Of Male Breast Mammary Carcinoma Male Breast Carcinoma Familial Cancer Of Breast Invasive Ductal Breast Carcinoma Breast Cancer Susceptibility Breast Cancer, Male, Susceptibility To Breast Cancer, Early-Onset, Susceptibility To Malignant Tumor Of The Breast Mammary Neoplasm Primary Breast Cancer Neoplasm Of Male Breast Carcinoma Of Breast Breast Cancer In Men Familial Breast Cancer Cancer Of Breast BC Breast Cancer Familial Breast Cancer Familial Male Breast Cancer, Familial Male Breast Male Carcinoma Breast Neoplasms Breast Neoplasms, Male Mammary Tumors Mammary Carcinomas Cancer, Breast Cancer, Breast, Susceptibility Invasive Breast Ductal Carcinoma Breast Neoplasm Susceptibility To Breast Cancer Mammary Neoplasms Animal Mammary Neoplasms Primary Malignant Neoplasm Of Breast Infiltrating Ductal Carcinoma Of Breast Infiltrating Duct Carcinoma Of Unspecified Site Infiltrating Ductular Carcinoma Of Unspecified Site Invasive Breast Carcinoma Of No Special Type Microinvasive Carcinoma Of Breast Carcinoma With Apocrine Differentiation
Influenza	Flu Influenza With Non-Respiratory Manifestation Influenza With Other Manifestations Influenza, Human Influenza, Susceptibility To Seasonal Influenza, Virus Identified
Oral Submucous Fibrosis	Oral Submucosal Fibrosis, Including Of Tongue Osmf Oral Cavity Submucous Fibrosis Oral Submucosal Fibrosis Submucosal Fibrosis
Peyronie Disease
Moyamoya Disease 1	Moyamoya Disease Spontaneous Occlusion Of The Circle Of Willis Mymy Progressive Intracranial Arterial Occlusion Moyamoya Syndrome MYMY1 Cerebrovascular Moyamoya Disease Moya-Moya Disease Progressive Intracranial Occlusive Arteropathy Idiopathic Moyamoya Disease
Osteoporosis	Postmenopausal Osteoporosis Osteoporosis, Postmenopausal Bone Mineral Density Quantitative Trait Locus Bmnd Osteoporosis, Involutional Osteoporosis, Susceptibility To Osteoporosis, Postmenopausal, Susceptibility Bone Mineral Density Variation Qtl, Osteoporosis OSTEOP Involutional Osteoporosis Senile Osteoporosis Osteoporosis Postmenopausal Bone Mineral Density, Quantitative Trait Locus Osteoporosis, Senile Idiopathic Osteoporosis Bone Rarefaction Nos Type 1 Osteoporosis
Breast Cyst	Cyst Of The Breast Breast Cysts
Renal Fibrosis
Autism	Autistic Disorder Autism Susceptibility 1 Childhood Autism Autistic Disorder Of Childhood Onset Infantile Autism Kanner'S Syndrome Autistic
Otosclerosis	Otospongiosis
Hepatitis B	Chronic Hepatitis B Hepatitis B Infection Serum Hepatitis HBV Hepatitis B Chronic Hbv, Susceptibility To Hepatitis B, Chronic Chronic Hepatitis B Without Delta Agent Chronic Hbv - [Hepatitis B Virus] Infection Hepatitis B Nos Chronic Type B Viral Hepatitis Hep B Nos
Communicating Hydrocephalus	Acquired Communicating Hydrocephalus
Sclerosteosis	Cortical Hyperostosis With Syndactyly Sost Cortical Hyperostosis-Syndactyly Syndrome
Lymphoid Interstitial Pneumonia	Lip Disease Lymphocytic Interstitial Pneumonia Lip Diseases LIP Disease Of Lips
Obstructive Nephropathy	Con Congenital Obstructive Nephropathy Nephropathy Obstructive
Hyperostosis	Hypertrophy Of Bone Bone Hypertrophy Bone Thickening Periosteum Thickening
Ovarian Cancer	Ovarian Carcinoma Ovarian Neoplasm Malignant Tumour Of Ovary Epithelial Ovarian Cancer Neoplasm Of Ovary Ovarian Neoplasms Ovarian Cancers Malignant Neoplasm Of Ovary Primary Malignant Neoplasm Of Ovary Ovarian Cancer, Somatic Malignant Ovarian Tumor Ovary Neoplasm Primary Ovarian Cancer Tumor Of The Ovary Cancer Of The Ovary Malignant Neoplasm Of The Ovary Malignant Tumor Of The Ovary Ovarian Malignant Tumor OC Ovarian Carcinomas Cancer, Ovarian Cancer Of Ovary Ovary Cancer Ca Ovary
Pulmonary Fibrosis	Fibrosis Of Lung
Glomerulonephritis	Bright'S Disease
Ureteral Disease	Ureteral Diseases Ureteral Disorders Disorder Of Ureter
Kidney Disease	Renal Failure Kidney Failure Kidney Diseases Nephropathy Abnormality Of The Kidney Impaired Renal Function Disease Renal Anomaly Kidney Dysfunction Renal Disease Nephropathies Renal Failure Adverse Event Abnormal Renal Function
Chronic Kidney Disease	Chronic Renal Disease Chronic Kidney Failure Ckd Chronic Renal Failure Kidney Failure, Chronic Chronic Renal Failure Syndrome Crf Renal Failure - Chronic Renal Failure Chronic Chronic Kidney Diseases Chronic Kidney Disease Stage 5 Ckd - [Chronic Kidney Disease] Crf - [Chronic Renal Failure] Chronic Kidney Impairment Chronic Renal Impairment Chronic Kidney Shutdown Chronic Hypoxic Kidney Failure Chronic Kidney Collapse Chronic Renal Insufficiency Chronic Kidney Toxaemia Chronic Kidney Hypofunction Chronic Renal Suppression Chronic Renal Failure, Stage 5 Ckd - [Chronic Kidney Disease] Stage 5 End Stage Kidney Failure End Stage Renal Failure End Stage Kidney Disease End Stage Renal Disease End Stage Chronic Renal Failure Esrf - [End Stage Renal Failure] Esrd - [End Stage Renal Diseases] Egfr - [Estimated Glomerular Filtration Rate] < 15 Ml/Min/1.73m²
Pneumoconiosis	Pneumoconioses Silicosis Nos Complicated Silicosis Fibrosis Of Lung With Silicosis Nodular Silicosis Pneumoconiosis Due To Silica Silicotic Fibrosis Of Lung Simple Silicosis Silicatosis Silicotic Lung Fibrosis Pneumoconiosis Due To Talc Pulmonary Talcosis Talc Lung Disease Talc Pneumoconiosis Talc Workers' Pneumoconiosis Talcosis Fibrosis Of Lung Due To Talc Asbestos Pneumoconiosis Amianthosis Asbestosis Lung Fibrosis With Asbestosis Pulmonary Asbestosis
Dacryoadenitis	Dacryocystitis
Heart Disease	Heart Failure Congenital Heart Disease Heart Diseases Congenital Heart Defects Congenital Heart Defect Congenital Anomaly Of Heart Heart Defect Heart Malformation Heart-Congenital Defect Congenital Heart Disorder Heart Defects Congenital Heart Defects, Congenital Heart Defects Heart Disease, Congenital Disease, Heart, Congenital Congestive Heart Failure
Gingival Disease	Gingival Diseases Gum Disease Gingival Disorder Gingivitis And Periodontal Diseases
Cholangiocarcinoma	Cholangiocarcinoma, Susceptibility To Extrahepatic Cholangiocarcinoma Intrahepatic Cholangiocarcinoma Chlc Chlc, Susceptibility To Cc Cholangiocarcinoma Of Biliary Tract Cholangiocellular Carcinoma Distal Cholangiocarcinoma Perihilar Cholangiocarcinoma Bile Duct Cancer Cca Adult Primary Cholangiocellular Carcinoma Bile Duct Carcinoma
Pancreatic Adenocarcinoma	Adenocarcinoma Of Pancreas Adenocarcinoma Of The Pancreas Pancreas Adenocarcinoma Malignant Exocrine Neoplasm Primary Pancreatic Adenocarcinoma Adenocarcinoma Of Islet Cell Of Pancreas Islet Cell Adenocarcinoma Of Unspecified Site Mixed Adenocarcinoma Islet Cell With Exocrine Of Unspecified Site
Hypertension, Essential	Essential Hypertension Hypertension High Blood Pressure Hypertension, Essential, Susceptibility To Hypertensive Disease Primary Hypertension EHT Hypertension, Salt-Sensitive Essential, Susceptibility To Hyperpiesia Idiopathic Hypertension Hypertensive Disorder Hypertension, Essential, Susceptibility To, 3 Hypertension, Essential 3 Hypertension, Essential, Salt-Sensitive Hypertension, Essential, Susceptibility To, 6 Hypertension, Essential 6 Hypertension, Salt-Sensitive Essential Hypertension, Susceptibility To Hypertension, Essential, Susceptibility To, 4 Hypertension, Essential 4 Hypertension, Essential, Susceptibility To, 2 Hypertension, Essential 2 Hypertension, Essential, Susceptibility To, 1 Hypertension, Essential 1 Hypertension, Essential, Susceptibility To, 5 Hypertension, Essential 5 Htn Vascular Hypertensive Disorder Systemic Primary Arterial Hypertension Hbp - [High Blood Pressure] Systemic Arterial Hypertensive Disorder Elevated Blood Pressure Arterial Hypertension Nos Hypertension Nos Benign Hypertension Systemic Arterial Hypertension Systemic Hypertension Artery Htn Benign Htn Vascular Htn Vascular Hypertension Cholesterol Hypertension Cholesterol Htn Idiopathic Htn Malignant Hypertension Malignant Htn Raised Blood Pressure Cardiovascular Hypertension Primary Htn - [Hypertension] High Arterial Tension High Blood Pressure Disorder Ht - [Hypertension] Htn - [Hypertension] Hypertensive Vascular Disease Hypertensive Vascular Degeneration
Sick Sinus Syndrome	Sinus Node Dysfunction Sinus Node Disease Sinus Node Infection Snd Sss Snd - [Sinus Node Dysfunction] Sinoatrial Node Dysfunction Sss - [Sick Sinus Syndrome] Sick Sinus Sick Sinus Tachycardia
Scoliosis
Autoimmune Disease	Autoimmune Diseases Autoimmune Hypersensitivity Disease Hypersensitivity Reaction Type Ii Disease Type Ii Hypersensitivity Reaction Disease
Colitis
Lung Cancer Susceptibility 3	Lung Adenocarcinoma Adenocarcinoma Of Lung LNCR3 Adenocarcinoma Of Lung, Susceptibility To Bronchogenic Lung Adenocarcinoma Nonsmall Cell Adenocarcinoma Adenocarcinoma Lung Lung Adenocarcinomas Non-Small Cell Adenocarcinoma
Fibrosarcoma	Neoplasms, Fibrous Tissue Fibrocytic Tumor Fibrosarcoma Of Soft Tissue Fibrous Tissue Neoplasm
Diabetes Mellitus	Diabetes
Vitreoretinopathy
Myopia	Near-Sightedness Short-Sightedness Nearsightedness Nearsighted Near Vision Close Sighted Myopic Short-Sighted Near Sighted
Dilated Cardiomyopathy	Familial Dilated Cardiomyopathy Primary Dilated Cardiomyopathy Idiopathic Dilated Cardiomyopathy Congestive Cardiomyopathy Idiopathic Dilation Cardiomyopathy Primary Familial Dilated Cardiomyopathy Cardiomyopathy, Dilated DCM Cardiomyopathy, Familial Dilated Dilated Cardiomyopathy, Familial Hypokinetic Dilated Cardiomyopathy, Familial Familial Idiopathic Cardiomyopathy Fdc Cardiomyopathy, Familial Idiopathic Idiopathic Cardiomegaly Dilated Congestive Cardiomyopathy Chronic Dilated Cardiomyopathy Ccm - [Congestive Cardiomyopathy] Cocm - [Congestive Cardiomyopathy] Dcm - [Dilated Cardiomyopathy] Dilated-Hypokinetic Cardiomyopathy Congestive Idiopathic Cardiomyopathy Primary Idiopathic Dilated Cardiomyopathy
Endometrial Cancer	Endometrial Carcinoma Endometrial Neoplasm Malignant Neoplasm Of Endometrium Endometrioid Carcinoma Endometrial Neoplasms Carcinoma, Endometrioid Endometrial Cancer, Familial Endometrial Carcinoma, Somatic Endometrial Cancer, Susceptibility To Endometrial Ca Malignant Endometrial Neoplasm Neoplasm Of Endometrium Primary Malignant Neoplasm Of Endometrium Tumor Of Endometrium Carcinoma Of The Endometrium Endometrioid Carcinoma Of Female Reproductive System ENDMC Carcinoma Endometrioid Endometrial Cancers Cancer, Endometrial Uterine Corpus Cancer
Urinary Tract Obstruction	Obstructive Uropathy Urinary Obstruction Urologic Diseases
Breast Disease	Breast Diseases

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Clinical Phase
Pre-clinical Phase

Clinical Phase

Inhibitory Antibodies (4)

Referencia número	Nombre del producto	Efecto	Pureza	Phase
HY-P99305	Metelimumab	Inhibitor	98.98%	Phase 2
HY-P991382	SAR-439459	Inhibitor	/	Phase 2
HY-P991383	LY2382770	Inhibitor	/	Phase 2
HY-P991950	SHR-1906	Inhibitor	/	Phase 2

Pre-clinical Phase

Bioactive Molecules (8)

Referencia número	Nombre del producto	Efecto	Pureza	Rare Diseases
HY-RS14435	TGFB1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-W764758	3-OH-Kynurenamine dihydroiodide	Activator	99.56%	Unkown
HY-RS14436	Tgfb1 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-147195	QH536	Inhibitor	/	Unkown
HY-156908	3-OH-Kynurenamine	Activator	/	Unkown
HY-RS14437	Tgfb1 Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS14438	TGFB1I1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-174534	Human TGFB1 mRNA		/	Unkown

Inhibitory Antibodies (2)

Referencia número	Nombre del producto	Efecto	Pureza	Rare Diseases
HY-P99606	Cirevetmab	Inhibitor	≥99.0%	Unkown
HY-P990517	Anti-TGFb1 Antibody	Inhibitor	98.24%	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	TGFB1	MGD	MGI:98725
Felis catus	TGFB1	VGNC	VGNC:66131
Macaca mulatta	TGFB1	VGNC	VGNC:78332
Bos taurus	TGFB1	VGNC	VGNC:35800
Rattus norvegicus	TGFB1	RGD	RGD:69051
Others	TGFB1	NCBI