JAK-IN-39
JAK-IN-39 (compound 11) is a JAK inhibitor that suppresses JAK1, JAK2, JAK3 with IC50 values of 0.05, 1.18, and 0.03 nM, respectively. JAK-IN-39 can inhibit the viability of TF-1 cells and also suppress the production of lymphocyte TNFα and INFγ in vitro.
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- No. CAS: 2250013-34-2
- Fòrmula: C25H26N10O2
- Peso molecular:498.54
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
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Actividad biológica
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JAK1 0.05 nM (IC50) |
JAK2 1.18 nM (IC50) |
JAK3 0.03 nM (IC50) |
Chemical Information
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No. CAS 2250013-34-2
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Peso molecular 498.54
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Fòrmula C25H26N10O2
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SMILES
COC1=NC(C2=NN3C(N[C@H]4C(C)(CN(C5=CC=C(N=N5)C#N)CC4)C)=C(C(N)=O)C=NC3=C2)=CC=C1
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
JAK-IN-39 Related Classifications
HY-170723 Related Classifications
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