Norcaesalpinin E
Based on 1 Customer Validation
Norcaesalpinin E, a C-17-norcassane-type diterpene found in Caesalpinia crista, is a Plasmodium falciparum growth inhibitor with an IC50 of 90 nM. Norcaesalpinin E induces dose-dependent growth inhibition of Plasmodium falciparum. Norcaesalpinin E can be used for the research of malaria.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza: 93%
- No. CAS: 854038-96-3
- Fòrmula: C21H28O6
- Peso molecular:376.44
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Almacenamiento:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Actividad biológica
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Chemical Information
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Actividad biológica
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Plasmodium 90 nM (IC50) |
Norcaesalpinin E (72 h) potently inhibits the growth of Plasmodium falciparum FCR-3/A2 clone in vitro with an IC50 of 90 nM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 854038-96-3
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Appearance Solid
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Peso molecular 376.44
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Fòrmula C21H28O6
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Color White to off-white
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SMILES
C[C@@]([C@@](C[C@@H]1O)(C2(C)C)O)([C@H](CC2)OC(C)=O)[C@](CC3=C4C=CO3)([H])[C@]1([H])C4=O
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Structure Classification
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Initial Source
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Pureza y Documentación
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Ficha de datos (286 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Instrucciones de manejo (2659 KB)
Referencias
[1]. Kalauni SK, et al. Antimalarial activity of cassane- and norcassane-type diterpenes from Caesalpinia crista and their structure-activity relationship. Biol Pharm Bull. 2006;29(5):1050-1052. [Content Brief]
[2]. Linn TZ, et al. Cassane- and norcassane-type diterpenes from Caesalpinia crista of Indonesia and their antimalarial activity against the growth of Plasmodium falciparum. J Nat Prod. 2005;68(5):706-710. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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