854038-96-3
Chemical Structure
Norcaesalpinin E
- CAS No.: 854038-96-3
- Formula:C21H28O6
- Molecular Weight:376.44
IUPAC Name: (1S,4aR,6S,6aS,11aS,11bS)-4a,6-dihydroxy-4,4,11b-trimethyl-7-oxo-1,2,3,4,4a,5,6,6a,7,11,11a,11b-dodecahydrophenanthro[3,2-b]furan-1-yl acetate
InChIKey: IBALQPBIWZLHPR-SJEMMDPOSA-N
SMILES: C[C@@]([C@@](C[C@@H]1O)(C2(C)C)O)([C@H](CC2)OC(C)=O)[C@](CC3=C4C=CO3)([H])[C@]1([H])C4=O
Biological Activity: Norcaesalpinin E, a C-17-norcassane-type diterpene found in Caesalpinia crista, is a Plasmodium falciparum growth inhibitor with an IC50 of 90 nM. Norcaesalpinin E induces dose-dependent growth inhibition of Plasmodium falciparum. Norcaesalpinin E can be used for the research of malaria[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Norcaesalpinin E | 93% | Norcaesalpinin E, a C-17-norcassane-type diterpene found in Caesalpinia crista, is a Plasmodium falciparum growth inhibitor with an IC50 of 90 nM. Norcaesalpinin E induces dose-dependent growth inhibition of Plasmodium falciparum. Norcaesalpinin E can be used for the research of malaria. | ||||||||||||||||||||
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References
- [1]. Kalauni SK, et al. Antimalarial activity of cassane- and norcassane-type diterpenes from Caesalpinia crista and their structure-activity relationship. Biol Pharm Bull. 2006;29(5):1050-1052. [Content Brief]
- [2]. Linn TZ, et al. Cassane- and norcassane-type diterpenes from Caesalpinia crista of Indonesia and their antimalarial activity against the growth of Plasmodium falciparum. J Nat Prod. 2005;68(5):706-710. [Content Brief]
