(R)-ACBI-4
(R)-ACBI-4 is an isomer of ACBI-4 (HY-176792). ACBI-4 is a selective GTP-loaded active state of KRAS (KRAS(on)) PROTAC degrader. ACBI-4 has significant anti-proliferative effect and potently degrades multiple KRAS mutants in cancer cells, such as KRASG12R.
(Pink: Ras ligand (HY-162960); Blue: VHL ligand (HY-176917); Black: linker).
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 3097973-97-9
- Fòrmula: C50H63N15O4S
- Peso molecular:970.20
-
Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Actividad biológica
-
Chemical Information
- Pureza y Documentación
- Referencias
-
Help & FAQs
Ver todos los productos específicos de isoformas PROTACs
More
Actividad biológica
|
VHL |
K-RAS |
Chemical Information
-
No. CAS 3097973-97-9
-
Peso molecular 970.20
-
Fòrmula C50H63N15O4S
-
SMILES
CC([C@H](N1N=NC2=C1CC[C@@H](CCCN3C[C@@H](N(CCC3)C4=NC(C5=NOC([C@@]6(C7=C(CCC6)SC(N)=C7C#N)C)=N5)=CC=N4)C)C2)C(N8C[C@@H](C[C@H]8C(NCC9=CC=C%10C(N(N=C%10)C)=C9)=O)O)=O)C
-
Envío
Room temperature in continental US; may vary elsewhere.
-
Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
(R)-ACBI-4 Related Classifications
HY-176792A Related Classifications
Powered by Bioz