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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
10 Results for "
ATTR
" in MedChemExpress (MCE) Product Catalog:
Products (10)
10 Results for "ATTR" in MCE Product Catalog:
1
1 Cited Publications
Referencia número: HY-148089
No. CAS: 1637600-16-8
Target:
Áreas de investigación:
Eplontersen is a triantennary N-acetyl galactosamine (GalNAc3-7a)-conjugated antisense oligonucleotide targeting transthyretin (TTR) mRNA to inhibit production of both variant and wild-type TTR protein. Misfolded TTR induces amyloid fibrils formation in the heart and peripheral nerves, leads to amyloid TTR (ATTR) amyloidosis diseases .
1
1 Cited Publications
Target:
Áreas de investigación:
Eplontersen sodium the sodium salt form of Eplontersen (HY-148089). Eplontersen sodium is a triantennary N-acetyl galactosamine (GalNAc3-7a)-conjugated antisense oligonucleotide targeting transthyretin (TTR) mRNA to inhibit production of both variant and wild-type TTR protein. Misfolded TTR induces amyloid fibrils formation in the heart and peripheral nerves, leads to amyloid TTR (ATTR) amyloidosis diseases .
1
1 Cited Publications
Referencia número: HY-P73580
Pureza: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TTR; Transthyretin; PALB; CTS1; HsT2651; CTS; Prealbumin, Amyloidosis Type I; ATTR; TBPA; Epididymis Luminal Protein 111; Thyroxine-Binding Prealbumin; Carpal Tunnel Syndrome 1; TTR Protein; Prealbumin; AMYLD1; HEL111; TTN
Species:
Mouse
Source:
HEK293
Referencia número: HY-P991128
No. CAS: 2965214-50-8
Synonyms: NI-006; ALXN2220
Target:
Áreas de investigación:
Cliramitug (NI-006; ALXN2220) is a monoclonal antibody that targets human transthyretin (TTR). Cliramitug binds to TTR and inhibits its amyloidogenic process, exerting amyloid formation-inhibiting activity. Cliramitug can be used in the research of transthyretin amyloidosis-related diseases, such as certain neurological and cardiovascular diseases .
Referencia número: HY-155299
Target:
Áreas de investigación:
PITB is a selective and orally active transthyretin (TTR) aggregation inhibitor. PITB can be used for transthyretin amyloidosis (ATTR) disease research .
Referencia número: HY-RS15238
Target:
Áreas de investigación:
TTR Human Pre-designed siRNA Set A contains three designed siRNAs for TTR gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Referencia número: HY-P70500
Pureza: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TTR; Transthyretin; PALB; CTS1; HsT2651; CTS; Prealbumin, Amyloidosis Type I; ATTR; TBPA; Epididymis Luminal Protein 111; Thyroxine-Binding Prealbumin; Carpal Tunnel Syndrome 1; TTR Protein; Prealbumin; AMYLD1; HEL111; TTN
Species:
Human
Source:
HEK293
Referencia número: HY-P71671
Pureza: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TTR; Transthyretin; PALB; CTS1; HsT2651; CTS; Prealbumin, Amyloidosis Type I; ATTR; TBPA; Epididymis Luminal Protein 111; Thyroxine-Binding Prealbumin; Carpal Tunnel Syndrome 1; TTR Protein; Prealbumin; AMYLD1; HEL111; TTN
Species:
Cynomolgus
Source:
HEK293
Referencia número: HY-P72026
Pureza: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TTR; Transthyretin; PALB; CTS1; HsT2651; CTS; Prealbumin, Amyloidosis Type I; ATTR; TBPA; Epididymis Luminal Protein 111; Thyroxine-Binding Prealbumin; Carpal Tunnel Syndrome 1; TTR Protein; Prealbumin; AMYLD1; HEL111; TTN
Species:
Human
Source:
HEK293
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
