2. Anti-infection
  3. Antibiotic Bacterial
  4. Geministatin B

Geministatin B is a potent antibiotic that can be found in the fungus Austroacremonium gemini MST-FP2131. Geministatin B exhibits antibacterial activity against Gram-positive bacteria including Bacillus subtilis, Staphylococcus aureus, and methicillin-resistant S. aureus (MRSA). Geministatin B can be used for the research of bacterial infections.

For research use only. We do not sell to patients.

Geministatin B

Geministatin B Chemical Structure

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Geministatin B Related Antibodies

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Description

Geministatin B is a potent antibiotic that can be found in the fungus Austroacremonium gemini MST-FP2131. Geministatin B exhibits antibacterial activity against Gram-positive bacteria including Bacillus subtilis, Staphylococcus aureus, and methicillin-resistant S. aureus (MRSA). Geministatin B can be used for the research of bacterial infections[1].

In Vitro

Geministatin B exhibits potent antibacterial activity against Bacillus subtilis (MIC = 0.39 µg/mL), Staphylococcus aureus (MIC = 3.1 µg/mL), and MRSA (MIC = 1.6 µg/mL)[1].
Geministatin B shows no antifungal activity against Saccharomyces cerevisiae with MIC > 200 µg/mL[1].
Geministatin B shows low cytotoxicity against mouse myeloma NS-1 cells (IC50 = 93 µM) and neonatal foreskin fibroblast cells (IC50 >190 µM)[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Geministatin B Related Antibodies
Molecular Weight

538.67

Formula

C32H42O7
SMILES

O=C(OC1=CC(O)=C(C(O)=O)C(C)=C1)C2=C(CCCCCCC/C=C\C/C=C\CCCCC)C=C(O)C=C2O
Structure Classification
Initial Source

Austroacremonium gemini
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Geministatin B Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Geministatin BAntibioticBacterialNR-PKS AquAStaphylococcus aureusmethicillin-resistant S. aureusBacillus subtilisGram-positive bacterianeonatal foreskin fibroblast cellsmyristoyl-CoAmouse myeloma NS-1 cellsAustroacremonium gemini MST-FP2131Saccharomyces cerevisiaeInhibitorinhibitorinhibit

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Geministatin B
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