PDE4A - phosphodiesterase 4A Gene

Species: Canis lupus familiaris (sub-species: familiaris)

Gene Type: protein coding
Gene ID: 100683695

About PDE4A

Primary_assembly 20: 51,196,595-51,241,799 reverse strand.ROS_Cfam_1.0:CM025119.1

This gene has 6 transcripts (splice variants), 261 orthologues and 22 paralogues.

PDE4A Products (5)

mRNA Protein Name
XM_038428649.1 XP_038284577.1 cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform X2
XM_038428650.1 XP_038284578.1 cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform X3
XM_038428648.1 XP_038284576.1 cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform X1
XM_038428651.1 XP_038284579.1 cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform X4
XM_038428652.1 XP_038284580.1 cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform X5

PDE4A Protein Structure

PDE4_UCR

PDE4_UCR: pfam18100 (177 - 292)

PDEase_I

PDEase_I: pfam00233 (431 - 671)

PHA03247

PHA03247: cl33720 (767 - 861)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 870 a.a.
Protein Preferred Names Protein Names

cAMP-specific 3',5'-cyclic phosphodiesterase 4A

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-B1639 Enoximone Inhibitor 99.91% Unkown

Clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Phase
HY-108047 MK-0873 Inhibitor 95.0% Phase 2
HY-106003 GSK356278 Inhibitor 99.82% Phase 1

Pre-clinical Phase

Bioactive Molecules (13)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-119190 PF-06445974 Inhibitor 98.59% Unkown
HY-16900A (R)-(-)-Rolipram Inhibitor 99.91% Unkown
HY-103050 ML-030 Inhibitor 99.28% Unkown
HY-131707 LEO 39652 Inhibitor 99.51% Unkown
HY-131340 LASSBio-1632 Inhibitor / Unkown
HY-114052 NVP-ABE171 Inhibitor / Unkown
HY-122167 L-869298 Inhibitor / Unkown
HY-134937 BC8-15 Inhibitor / Unkown
HY-179504 PDE4B-IN-6 Inhibitor / Unkown
HY-201403 LY2775240 Inhibitor / Unkown
HY-RS10220 PDE4A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS10221 Pde4a Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS10222 Pde4a Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens PDE4A NCBI NCBI:5141