MUC12 - mucin 12, cell surface associated Gene
Also Known as MUC11; MUC-11; MUC-12
Species: Homo sapiens
About MUC12
Restricted expression toward colon (RPKM 48.0).
Summary
This gene encodes an integral membrane glycoprotein that is a member of the Mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces and have been implicated in epithelial renewal and differentiation. These glycoproteins also play a role in intracellular signaling. This protein is expressed on the apical membrane surface of epithelial cells that line the mucosal surfaces of many different tissues including the colon, pancreas, prostate, and uterus. The expression of this gene is downregulated in colorectal Cancer tissue. [provided by RefSeq, Apr 2017]
MUC12 Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_001164462.2 | NP_001157934.1 | mucin-12 precursor |
MUC12 Protein Structure
SEA: SEA domain (5173 - 5268)
- 0
- 900
- 1800
- 2700
- 3600
- 4500
- 5478 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
mucin-12 |
|
MUC12 Antibodies
| Cat. No. | Product Name | Application | Reactivity |
|---|---|---|---|
| HY-P84873 | MUC12 Antibody (YA4570) | ICC/IF, FC, ELISA | Human |
| HY-P84873A | MUC12 Antibody (YA4570)(PBS only) | ICC/IF, FC, ELISA | Human |
| HY-P84874 | MUC12 Antibody (YA4571) | IHC-P, FC, ELISA | Human |
| HY-P84874A | MUC12 Antibody (YA4571)(PBS only) | IHC-P, FC, ELISA | Human |
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Colorectal Cancer |
|
|
| Ulcerative Colitis |
|
|
| Colitis |
|
|
| Crohn'S Disease |
|
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-RS08832 | MUC12 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
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