MUC12 Antibody (YA4571)

(Synonyms: MUC11; MUC-11; )

MUC12 Antibody (YA4571) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to MUC12.

For research use only. We do not sell to patients.
  • Host:

    Mouse

  • Isotype:

    IgG1

  • Application:

    IHC-P, FC, ELISA

  • Reactivity :

    Human

  • Formulation:

    Supplied in PBS with 0.05% sodium azide

  • Conjugation:
    Non-conjugated

Applications

Application
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
FC Info
FC: Flow Cytometry
ELISA Info
ELISA: Enzyme Linked Immunosorbent Assay
Dilution Ratio 1:200-1:1000 1:200-1:400 1:10000

Product Details

Description

MUC12 Antibody (YA4571) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to MUC12.

  • Host Mouse
  • Clonality Monoclonal
  • Species Reactivity
    Human
  • Calculated Molecular Weight Predicted band size: 55.8 kDa
Immunogen

Purified recombinant fragment of human MUC12 (AA: extra 371-592) expressed in HEK293-6e cells supernatant.

Purification

affinity purified.

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG1

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in PBS with 0.05% sodium azide

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    MUC12 is involved in epithelial cell protection, adhesion modulation, and signaling. May be involved in epithelial cell growth regulation. Stimulated by both cytokine TNF-alpha and TGF-beta in intestinal epithelium

  • Subcellular Localization

    Membrane; Single-pass type I membrane protein

  • Expression


    Tissue_specificity:It is widely distributed and highly expressed in the colon. Its expression is downregulated in the colon of patients with colorectal cancer, ulcerative colitis (UC) , and Crohn's disease (CD) .

    Induction:By listeriolysin O

  • Isoforms & Post-Translational Modification

    Q9UKN1 has 2 isomers: Q9UKN1-1: 558164 Da (predicted); Q9UKN1-2: 542703 Da (predicted).

  • SwissProt ID

    Q9UKN1

  • Gene ID
  • Synonyms

    MUC11; MUC-11;

MUC12 Antibody (YA4571) Related Classifications

MOQ
Minimum order quantity
100 mg

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