MUC12 Antibody (YA4571)
(Synonyms: MUC11; MUC-11; )MUC12 Antibody (YA4571) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to MUC12.
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Host:
Mouse
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Isotype:
IgG1
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Application:
IHC-P, FC, ELISA
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Reactivity :
Human
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Formulation:
Supplied in PBS with 0.05% sodium azide
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Conjugation:
Non-conjugated
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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FC
FC: Flow Cytometry
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ELISA
ELISA: Enzyme Linked Immunosorbent Assay
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|---|---|---|---|
| Dilution Ratio | 1:200-1:1000 | 1:200-1:400 | 1:10000 |
Product Details
MUC12 Antibody (YA4571) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to MUC12.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
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Calculated Molecular Weight Predicted band size: 55.8 kDa
Purified recombinant fragment of human MUC12 (AA: extra 371-592) expressed in HEK293-6e cells supernatant.
affinity purified.
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS with 0.05% sodium azide
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
MUC12 is involved in epithelial cell protection, adhesion modulation, and signaling. May be involved in epithelial cell growth regulation. Stimulated by both cytokine TNF-alpha and TGF-beta in intestinal epithelium
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Subcellular Localization
Membrane; Single-pass type I membrane protein
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Expression
Tissue_specificity:It is widely distributed and highly expressed in the colon. Its expression is downregulated in the colon of patients with colorectal cancer, ulcerative colitis (UC) , and Crohn's disease (CD) .
Induction:By listeriolysin O -
Isoforms & Post-Translational Modification
Q9UKN1 has 2 isomers: Q9UKN1-1: 558164 Da (predicted); Q9UKN1-2: 542703 Da (predicted).
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SwissProt ID
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Synonyms
MUC11; MUC-11;
Documentation